Early-phase 18F-FP-CIT PET images: a promising imaging biomarker for predicting early dementia conversion in Parkinson’s disease
Objective: This study aims to investigate whether early-phase 18F-N-(3-fluoropropyl)-2β-carboxymethoxy-3β-(4-iodophenyl) nortropane (18F-FP-CIT) positron emission tomography (PET) images (i.e., images acquired within the first 10 min after…Novelty Seeking: A Narrative Review
Objective: To explore novelty seeking (NS) as a construct, in both its adaptive and maladaptive roles, in order to provide insight into the cognitive and…Evaluation of possible pre-motor symptoms of Parkinson’s disease in a GBA-mutation positive cohort, as well as Gaucher disease patients.
Objective: To clinically evaluate a cohort of healthy glucocerebrosidase (GBA) mutation carriers in search of early biomarkers for neurodegeneration that may be prodromal features of…Atypical Manifestations of Subacute Sclerosing Panencephalitis (SSPE): A Case Series from India
Objective: To report unusual manifestations Subacute Sclerosing Panencephalitis. Background: Subacute Sclerosing Panencephalitis (SSPE) is a slow viral infection caused by measles virus resulting in progressive…Salivary α-synuclein in Parkinson’s disease – a pilot study
Objective: The aim of our study was to measure total salivary α-synuclein in Parkinson´s disease (PD) patients to assess its potential as a biomarker of…Development of therapeutic substances for the disassembly of α-synuclein aggregates as disease-modifying treatment of synucleinopathies
Objective: Development of high-affinity ligands to α-synuclein (α-syn) for a therapeutic approach aiming for the disassembly of α-syn aggregates as a disease-modifying treatment of synucleinopathies.…Diagnostic and treatment burden of dystonia in Turkey: a patient journey map
Objective: To assess the burden of access to diagnosis and botulinum neurotoxin (BoNT) treatment in Turkish patients with dystonia and hemifacial spasm (PwD/HFS). Background: Diagnostic…REM sleep behaviour disorder in Parkinson’s disease: prevalence and correlation with other sleep parameters
Objective: to assess the prevalence of probable rapid eye movement (REM) sleep behavior disorder (RBD) in Parkinson’s disease (PD) patients and its correlation with other…Weighing tremor reduction and side effects: Impact of efficacy and safety outcomes on patient satisfaction at 6 months in MR-guided focused ultrasound thalamotomy for tremor treatment
Objective: To relate efficacy and safety outcomes to patient satisfaction at 6 months after MR-guided focused ultrasound (MRgFUS) thalamotomy in the ventral intermediate nucleus (VIM)…Parkinson’s Progression Markers Initiative (PPMI): Defining PD biology to accelerate PD therapeutics
Objective: The overall goal of PPMI is to identify, test and validate biomarkers of PD to accelerate therapeutic development throughout the PD continuum. Background: PPMI…
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