A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson’s Disease (PADOVA): Rationale, Design, and Baseline Data
Objective: The study will evaluate the efficacy and safety of prasinezumab in individuals with early-stage Parkinson's disease (PD) on stable symptomatic therapy. Background: Available treatments…Quantitative gait analysis to evaluate changes in gait pattern after Botulinum toxin A injection by hemiparesis
Objective: This retrospective study aimed to assess the effect of Botulinum toxin A (BoNT-A) injections in the lower limbs of hemiparetic patients on gait parameters,…An European-Canadian multinational evaluation of access to care in Parkinson disease: a patient perspective
Objective: To provide a multi-national perspective of people with Parkinson disease (PwPD) on access to healthcare and the impact of the COVID-19 pandemic on those…Dystonia in the Middle East – The Cleveland Clinic Abu Dhabi Experience
Objective: This study aimed to evaluate the clinical spectrum of patients with dystonia seen at Cleveland Clinic Abu Dhabi Hospital (CCAD), a tertiary care center…Enhanced sensitivity to bradykinesia progression using digital health technologies in early Parkinson’s disease
Objective: To evaluate the sensitivity of digital biomarkers of bradykinesia to longitudinal progression relative to MDS-UPDRS sub-scores in early-stage Parkinson’s disease (PD). Background: It is…Predictors of death in Parkinson’s disease
Objective: To investigate how clinical, motor and behavioural characteristics impact on Parkinson mortality in a cohort from a tertiary movement disorders specialty center . Background:…Paraneoplastic cerebellar degeneration due to an anti-SOX 1 antibody manifesting as head tremors, without evidence of underlying malignancy
Objective: To describe a case of Paraneoplastic Cerebellar degeneration (PCD) linked to anti-SOX 1 antibody with no discernible malignancy. Background: PCD is a rare neurological…Actigraphy wear compliance across CNS disorders
Objective: Examine actigraphy wear compliance in 5 neurological-disorders clinical trials using an ActiGraph GT9X Link with additional compliance features Background: Wrist worn biometric devices are…Gene rearrangement as the cause of hereditary Hypomyelinating Leukodyistrophy disease type 5 (HLD5)
Objective: To define the clinical, neurophysiological, neuroimaging and pathological findings from a patient carrying a FAM126A homozygous exon 3-7 deletion. Background: Hypomyelinating leukodystrophies constitute a…Manifestations of aging and Parkinson’s Disease in low-frequency fluctuations of postural sway velocity
Objective: To distinguish the effects of aging and Parkinson's disease on balance control. Background: Many balance control measures are derived from spontaneous fluctuations of the center…
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