MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2023 International Congress

    Novelty Seeking: A Narrative Review

    K. Paulk, L. Neilson (Portland, USA)

    Objective: To explore novelty seeking (NS) as a construct, in both its adaptive and maladaptive roles, in order to provide insight into the cognitive and…
  • 2023 International Congress

    Evaluation of possible pre-motor symptoms of Parkinson’s disease in a GBA-mutation positive cohort, as well as Gaucher disease patients.

    L. Brodin, P. Svenningsson (Stockholm, Sweden)

    Objective: To clinically evaluate a cohort of healthy glucocerebrosidase (GBA) mutation carriers in search of early biomarkers for neurodegeneration that may be prodromal features of…
  • 2023 International Congress

    Atypical Manifestations of Subacute Sclerosing Panencephalitis (SSPE): A Case Series from India

    G. Harikrishna, K. Mala, SK. Kodapala (MANDYA, India)

    Objective: To report unusual manifestations Subacute Sclerosing Panencephalitis. Background: Subacute Sclerosing Panencephalitis (SSPE) is a slow viral infection caused by measles virus resulting in progressive…
  • 2023 International Congress

    Salivary α-synuclein in Parkinson’s disease – a pilot study

    M. Kaiserova, D. Hrabos, M. Levkova, M. Kavalkova, R. Kopacik, K. Mensikova, P. Kanovsky (Olomouc, Czech Republic)

    Objective: The aim of our study was to measure total salivary α-synuclein in Parkinson´s disease (PD) patients to assess its potential as a biomarker of…
  • 2023 International Congress

    Development of therapeutic substances for the disassembly of α-synuclein aggregates as disease-modifying treatment of synucleinopathies

    A. Willuweit, M. Sevenich, G. Tamgüney, J. Mohrlüder, D. Willbold (Düsseldorf, Germany)

    Objective: Development of high-affinity ligands to α-synuclein (α-syn) for a therapeutic approach aiming for the disassembly of α-syn aggregates as a disease-modifying treatment of synucleinopathies.…
  • 2023 International Congress

    Diagnostic and treatment burden of dystonia in Turkey: a patient journey map

    R. Yilmaz, N. öksüz, B. Samancı, A. Acarer, M. Ceylan, N. Durmaz-Celik, H. Erdem, S. özkan, H. Hanağası, O. Doğu, C. Akbostancı (Ankara, Turkey)

    Objective: To assess the burden of access to diagnosis and botulinum neurotoxin (BoNT) treatment in Turkish patients with dystonia and hemifacial spasm (PwD/HFS). Background: Diagnostic…
  • 2023 International Congress

    REM sleep behaviour disorder in Parkinson’s disease: prevalence and correlation with other sleep parameters

    S. Diaconu, L. Ungureanu, A. Zarnoveanu, B. Ciopleias, V. Vasile, A. Iacob, T. Moldovan, C. Falup-Pecurariu (Brasov, Romania)

    Objective: to assess the prevalence of probable rapid eye movement (REM) sleep behavior disorder (RBD) in Parkinson’s disease (PD) patients and its correlation with other…
  • 2023 International Congress

    Weighing tremor reduction and side effects: Impact of efficacy and safety outcomes on patient satisfaction at 6 months in MR-guided focused ultrasound thalamotomy for tremor treatment

    F. Buechele, S. Mahendran, M. Uhl, C. Freudinger, A. Maric, M. Oertel, C. Baumann, L. Stieglitz (Zurich, Switzerland)

    Objective: To relate efficacy and safety outcomes to patient satisfaction at 6 months after MR-guided focused ultrasound (MRgFUS) thalamotomy in the ventral intermediate nucleus (VIM)…
  • 2023 International Congress

    Parkinson’s Progression Markers Initiative (PPMI): Defining PD biology to accelerate PD therapeutics

    B. Mcmahon, A. Siderowf, T. Simuni, C. Tanner, B. Mollenhauer, C. Coffey, D. Galasko, K. Posten, L. Chahine, R. Dobkin, T. Froud, K. Kieburtz, D. Weintraub, K. Merchant, M. Frasier, T. Sherer, S. Chowdhury, E. Brown, R. Alcalay, A. Videnovic, K. Fabrizio, E. Flagg, K. Marek (New Haven, USA)

    Objective: The overall goal of PPMI is to identify, test and validate biomarkers of PD to accelerate therapeutic development throughout the PD continuum. Background: PPMI…
  • 2023 International Congress

    National Luxembourg Sleep Study: An enriched, at risk, prodromal Parkinson’s Disease cohort

    D. Mcintyre, L. Pavelka, C. Pauly, G. van Cutsem, O. Tsurkalenko, T. Marques, C. Gomes, S. Jonsdottir, J. Welch, K. Gunter, G. Aguayo, A. Sharify, E. Rosalès-Jubal, M. Vaillant, V. Satagopam, S. Ghosh, C. Vega Moreno, K. Roomp, A. Pincherle, M. Gantenbein, N. Diederich, M. Hu, R. Krüger, L. Vilas Boas (Luxembourg, Luxembourg)

    Objective: To identify a cognitively intact enriched cohort of people with isolated rapid eye movement (iREM) sleep behaviour disorder (iRBD) and hyposmia, at risk of…
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