The role of the default mode network and striatal circuits in the expression of depressive symptoms in premanifest Huntington’s disease
Objective: This study aimed to investigate changes in large-scale network effective connectivity of the default mode network (DMN) and striatum in the expression of depression…Integrative analysis of fecal metabolomics and metagenomics for Parkinson’s disease
Objective: The objectives of the current study were to explore how the fecal metabolomics changed, and how they interacted with the alteration of microbiota in…Apathy and impulsivity co-occur in Huntington’s disease
Objective: To determine whether apathy and impulsivity co-occur in people with Huntington’s disease. Background: Apathy and impulsivity are debilitating behavioural changes which often occur in…Automated VMAT2 [18F]AV-133 PET analysis in Parkinson’s disease
Objective: To evaluate a fully automated image analysis pipeline to process vesicular monoamine transporters type 2 (VMAT2) [18F]AV-133 tracer positron emission tomography (PET) images, by…Hemi-dystonia secondary to encephalitis and its response to staged pallidotomy
Objective: Reporting a case of hemi-dystonia (with involvement of trunk) secondary to encephalitis and its response to staged bilateral pallidotomy. Background: In the Axis 1…Measuring the heterogeneity of disease progression in Parkinson’s disease with multimodal clinical milestones over 10 years in the DeNoPa cohort
Objective: To provide a reference of individual Parkinson’s disease (PD) progression by assessing multimodal milestones over 10 years (y) in patients of the DeNoPa cohort.…Premenstrual worsening of UPDRS motor scale in women affected by Parkinson’s Disease
Objective: The role of estrogen in dopaminergic pathways and the premenstrual worsening of parkinsonian symptoms. Background: Female sex hormones, during the menstrual cycle, could influence…Association of sex with health-related quality of life in adults with chronic tic disorders
Objective: To investigate if there was an association of sex with health-related quality of life (HR-QOL) and psychiatric comorbidities in adults with Tourette syndrome (TS)…Enrollment phase sensing data from the Adaptive DBS Algorithm for Personalized Therapy in Parkinson’s Disease (ADAPT-PD) clinical trial
Objective: To describe enrollment sensing data from the Adaptive DBS Algorithm for Personalized Therapy in Parkinson’s Disease (ADAPT-PD) trial (NCT04547712). Background: Local field potential (LFP)…Subtyping Parkinson’s disease: Quality of life changes after subthalamic stimulation depend on nonmotor and motor symptoms
Objective: To investigate if patients with Parkinson’s disease (PD) undergoing subthalamic stimulation (STN-DBS) can be clustered in different subtypes based on demographic, motor and non-motor…
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