Cognitive underside of Parkinson’s Disease: A working memory updating failure in freezing of gait
Objective: To investigate the role of components of working memory updating in freezing of gait phenomenon Parkinson’s Disease Background: The role of cognitive deficits has…Development and preliminary results of a new picture-based self-rating tool for neuropsychiatric syndromes in Parkinson’s disease
Objective: To develop a picture-based, non-verbal screening tool to detect neuropsychiatric syndromes (NPS), including depression, anxiety, apathy, fatigue, mania, impulse control disorder (ICD), sleeping problems,…A benign course of Parkinson’s disease associated with different mutations in the glucocerebrosidase gene – a case series
Objective: Herein we describe 5 cases of GBA-related PD patients with a markedly benign course. Background: Subjects carrying mutations in the GBA1 gene, whether in…The Synuclein-One Study: Detection of Cutaneous Phosphorylated alpha-synuclein for the Diagnosis of the Synucleinopathies
Objective: The Synuclein-One study is an NIH-funded 30-site, multicenter trial of 428 patients with synucleinopathies including Parkinson’s disease (PD), dementia with Lewy bodies (DLB), multiple…Narcolepsy type 1, supranuclear vertical gaze palsy, and agrypnia excitata in a patient with anti-Ma associated encephalitis.
Objective: To describe a case of a patient with narcolepsy type 1, supranuclear vertical gaze palsy, and agrypnia excitata, who presented with anti-Ma encephalitis. Background:…Effect of levodopa on the interpretation of social interactions in people living with Parkinson’s disease
Objective: Better understand the social interactions by assessing the effect of oral levodopa on the social cognition abilities in fluctuating PD patients without significant cognitive disorder.…Jaw opening myoclonus in Subacute Sclerosing Panencephalitis: A new phenotypic observation which may be a diagnostic clue
Objective: We aimed to study the frequency of jaw myoclonus in subacute sclerosing panencephalitis (SSPE). Background: SSPE is a rare disorder due to mutant measles…Sex differences for off episodes in Parkinson’s disease
Objective: To determine the sex differences for the frequency, duration, and impact of off episodes in Parkinson’s disease (PD). Background: Dopamine replacement therapy through oral…Management of Sigmoid Volvulus in Parkinson’s patients presenting to Royal Berkshire Hospital, Reading ,UK.
Objective: To evaluate acute management of volvulus in Parkinson’s Background: Constipation affects upto 50% of patients with Parkinson's and sigmoid volvulus is an under recognized…How to dose extended-release carbidopa-levodopa capsules (IPX203) in Parkinson’s disease patients: Experience from the Phase 3 clinical trial
Objective: To provide guidance on dosing of IPX203 based on clinical trial experience. Background: IPX203 is an extended-release, oral carbidopa-levodopa (CD-LD) formulation designed to rapidly…
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