Effort-based decision-making and neuropsychiatric symptoms before and after subthalamic nucleus deep brain stimulation in Parkinson’s disease
Objective: Parkinson’s disease patients with apathy and patients in the medication OFF state show reduced reward sensitivity in effort-based decision-making tasks. The effect of subthalamic…The neuroprotective properties of NLX-112 in MPTP treated mice are mediated by reactive gliosis and astrocytic GDNF
Objective: To investigate whether NLX-112, a potent and selective 5-HT1A agonist is neuroprotective in a mouse MPTP model of Parkinson’s Disease (PD) [1]. Background: There…Multiple N-of-1 trials to investigate hypoxia-based treatment in Parkinson’s disease: safety and short-term effects
Objective: In this study, we describe the safety and short-term effects of the first hypoxia-based treatment trial in Parkinson’s disease by deploying a personalized multiple…Combination COMT inhibitor with Levodopa reduces consumption of vitamin B6
Objective: To investigate changes in Levodopa (LD) pharmacokinetics and changes in homocysteine, vitamin B6, and vitamin B12 in Parkinson's disease (PD) patients receiving LD formulations…Beta LFP Power Change After Levodopa Intake in Parkinson’s Disease Patients with Chronic Sensing-Enabled DBS Systems
Objective: To study the relationship between oscillatory beta activity in the subthalamic nucleus (STN) and the intake of dopaminergic medication in a group of Parkinson’s…Fragile X Related Tremor in FMR1 Premutation Women without FXTAS
Objective: To determine whether there is a FMR1 premutation associated tremor in women who do not meet criteria for Fragile X-associated tremor ataxia syndrome (FXTAS)…Response to Levodopa in Parkinson´s Disease Over Time. A 4-year Follow-up Study.
Objective: The aim of the present study was to analyze the response to levodopa in Parkinson´s disease (PD) patients with motor fluctuations followed up for…Correlation between hemoglobin level and disease severity in patients with Parkinson’s disease
Objective: Objective of this study was to investigate the potential correlation between hemoglobin levels and Parkinson's disease (PD) severity, and to compare them with a…Clinical spectrum, imaging characteristics and care giver burden assessment of early onset non-dominant progressive cerebellar ataxias
Objective: To characterise the phenotypic and radiological spectrum of patients with early onset non-dominant progressive cerebellar ataxias and to assess the impact of the disease…Musical Perception in Parkinson’s Disease, a Pilot Study
Objective: This pilot study aimed to investigate whether patients with PD have deficits in the perception of melody, rhythm, and musical excerpt recognition as measured…
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