Co-designing Digital Technologies to improve Clinical Care in People with Parkinson’s Disease
Objective: To develop a co-design methodology and test the usability and acceptability of three digital health technologies for people with Parkinson’s Disease (PwP) Background: The…The impact of STN-DBS on brain metabolic activity during dynamic obstacle avoidance in Parkinson’s disease
Objective: To describe brain metabolic activity changes during dynamic obstacle avoidance in parkinsonian patients with subthalamic deep brain stimulation (STN-DBS) Background: STN-DBS does not offer…Gender differences in REM Sleep Behavior Disorder in Parkinson’s disease
Objective: To study the gender differences in probable REM Sleep Behavior Disorder (RBD) and other sleep characteristics in a cohort of Parkinson’s disease (PD) patients.…The pivotal role of dual tracer (FDG + DOPA) PET MRI brain for diagnosis of MSA-C.
Objective: This case report demonstrates the potential of dual-tracer imaging (FDG + DOPA) PET MRI brain in diagnosing and distinguishing the patients with MSA-C from atypical…PFBC and dystonia: description of a cohort and peculiar cases
Objective: To describe dystonia in a PFBC cohort Background: Primary familial brain calcification (PFBC) is a rare neurodegenerative disorder characterized by calcium deposition in basal…DaT-Scans Have Limited Utility in Predicting Treatment Response to Ventriculoperitoneal Shunts in Normal Pressure Hydrocephalus
Objective: To determine usefulness of DaT-SPECT imaging in the management of normal pressure hydrocephalus (NPH). Background: Dopamine transporter single-photon emission computed tomography (DaT-SPECT) imaging is…Frequency of SCA 2, 3 and 7 in Slovak patients with spinocerebellar ataxia – first report of SCA2 patient from Slovakia
Objective: The aim of this study is to investigate the frequency of spinocerebellar ataxia (SCA) 2, 3 and 7 among Slovak patients with cerebellar ataxia…Bradykinesia in Patients with Cervical Dystonia: Objective Assessment with Optical Sensor
Objective: To objectively quantify selected parameters of bradykinesia investigated by finger tapping in cervical dystonia patients using the Leap Motion Controller (LMC) sensor. Background: Bradykinesia,…Integrated analysis of phase 3 trials of foslevodopa/foscarbidopa demonstrated that majority of reported infusion site AEs including infections were non serious, mild to moderate in severity and did not result in treatment discontinuation.
Objective: To characterize reported infusion site infection adverse events (AEs) and their clinical management in patients with Parkinson’s disease (PD) treated with foslevodopa/foscarbidopa (LDP/CDP). Background:…Evaluating the efficacy of dextromethorphan/quinidine (DM/Q) in treating irritability in Huntington’s disease
Objective: To prove the efficacy and safety of dextromethorphan/quinidine 20mg/10mg (Nuedexta®) in patients with irritability due to HD. Background: Irritability is one of HD's most…
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