Why is HAL effective in improving gait and balance function in Parkinson’s disease?
Objective: We performed rehabilitation using a Hybrid Assisted Limb (HAL) for PD and found that gait and balance functions improved before and after HAL rehabilitation.…Gray matter volume changes in occipital and temporal visual brain region are associated with freezing of gait in Parkinson’s
Objective: This study aimed to investigate the association of changed gray matter volume(GMV)with Freezing of gait(FOG) in Parkinson’s disease(PD). Background: FOG is a characteristic gait…Predicting ALS progression using remote sensor-based assessments
Objective: To develop a predictive model of amyotrophic lateral sclerosis (ALS) progression using self-administered digital assessments. Background: Remote fit-for-purpose sensor-based assessments stand to enhance the…Jumping to Conclusions bias, psychosis and impulsivity in early stages of Parkinson’s disease
Objective: The aim was to explore the correlations between Jumping to Conclusions (JtC) tendency and neuropsychiatric features in patients with early Parkinson’s disease (PD). Background:…Placebo response in Parkinson’s disease (PD) is predicted by expression levels of a specific brain network
Objective: To determine whether baseline expression levels for the previously validated sham surgery-related metabolic pattern (SSRP) can be used to predict the magnitude of the…Neuropsychological and quality of life outcome comparison after awake and asleep pallidal deep brain stimulation (DBS) surgery for Parkinson’s disease
Objective: To compare cognitive, psychiatric and quality of life (QoL) outcomes after awake and asleep bilateral pallidal (GPi) deep brain stimulation (DBS). Background: Prior studies…SAFE-DBS – A monocentric, randomised, blind evaluation of safinamide in the perioperative period in Parkinsonian patients with deep brain stimulation
Objective: This monocentric, randomised, blind study is designed to evaluate the effect of safinamide on motor and neuropsychiatric symptoms in the 3 month perioperative period…Real-life monitoring of Parkinson’s disease tremor: does the non-tremor subtype really exist?
Objective: To quantify daily-life tremor in Parkinson’s disease (PD) using a smartwatch containing a three-axis accelerometer and gyroscope. Background: Objective and continuous evaluation of PD…Altered brain energetics in Parkinson’s Disease: a multimodal neuroimaging study
Objective: To investigate patterns of altered brain energetics in Parkinson’s disease (PD). Background: Alterations in mitochondrial function, related to brain energetics, may play an important…Preliminary Report on the Safety and Tolerability of Allogeneic Bone marrow-derived Mesenchymal Stem Cells as a disease-modifying therapy for Parkinson’s disease: Phase IIa double-blind, randomized controlled trial
Objective: To select the safest and most effective number of repeat doses of allogeneic mesenchymal stem cells (MSC) purified from bone marrow-derived from a healthy…
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