Normative values for the Instrumented Timed Up and Go test in Parkinsonian populations
Objective: This study aims to define normative values for the Instrumented Timed Up and Go test using wearable inertial sensors in people affected by Parkinson’s…Evaluating continuous monitoring in Parkinson’s disease through real-world, device-reported outcomes.
Objective: This work presents an analysis of real-world, device-reported outcomes from patients in Greece, following a 6-month, continuous telemonitoring paradigm for Parkinson's disease. Results show…Incremental Hospitalizations and Associated Costs of Co-existing Dementia in Patients with Parkinson’s Disease Psychosis: An analysis of US Medicare Beneficiaries
Objective: To evaluate incremental hospitalizations and costs among Medicare patients with Parkinson's disease psychosis (PDP) vs. PDP+dementia (PDP+D). Background: Research examining hospitalizations and costs of…Epigenetic clock acceleration is linked to earlier onset and phenoconvertion of Rapid-eye-movement sleep behavior disorder
Objective: In the current study, we aim to evaluate whether Rapid-eye-movement sleep behavior disorder (RBD) age-at-onset and age-at-phenoconversion are associated with DNA methylation-age acceleration (DNAm-AA).…Exosomal α-synuclein in Multiple system atrophy and parkinson’s disease cause distinct synucleinopathies
Objective: In this study, we investigated the differences in exosomal α-syn between MSA and PD patients. Background: Parkinson's disease (PD) and multiple system atrophy (MSA)…Asymmetric synaptic density and glucose consumption in subjects with non-demented Parkinson’s Disease, as measured with [11C]UCB-J and [18F]FDG PET.
Objective: The objective of this study was to investigate asymmetric synaptic density and glucose consumption in moderate-stage non demented PD patients and the association between…Cortical thickness and global atrophy progression in Parkinson’s disease with probable RBD
Objective: To explore 3-year cortical thickness (CTh) and global atrophy progression in treated Parkinson’s disease (PD) with probable REM sleep behavior disorder (RBD). Background: Parkinson’s…Efficacy and safety of Mexiletine versus Placebo in patients with myotonia: A Systematic Review and Meta-analysis
Objective: We conducted this study to be the first systematic review and meta-analysis to investigate the efficacy and safety of mexiletine in the treatment of patients…Optimal topographic characteristics of focused ultrasound unilateral thalamotomy for tremor-dominant Parkinson´s disease
Objective: To define topography that correlates with tremor control after unilateral focused ultrasound (FUS) thalamotomy for tremor-dominant Parkinson´s Disease (TDPD). Background: Unilateral FUS thalamotomy of…Challenges in patient-physician communication during limited time appointments in Parkinson’s disease
Objective: Our aim is to analyze challenges in patient-physician communication during limited time appointments in Parkinson’s disease (PD). Background: Due to limited number of movement…
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