GAD-Positive Versus GAD-Negative Stiff Person Syndrome: A Retrospective Study
Objective: Delineate demographic and clinical differences between GAD-65-antibody positive (seropositive) and negative (seronegative) SPS. Background: Elevated Glutamic Acid Decarboxylase 65 antibody (GAD-65 Ab) titers are…Dandy-Walker syndrome. A case study.
Objective: Present a case study with rare congenital disease for further сreating a database and developing algorithms for the management of such cases in the…Altered activity of lysosomal hydrolases in monocyte-derived macrophages as potential biomarker for differential diagnosis of multiple system atrophy
Objective: The aim was to assess the possibility of differentiating synucleinopathies (Parkinson’s disease (PD), dementia with Lewy bodies (DLB), multiple system atrophy (MSA) by lysosomal…Safety and Efficacy of the Anti-alpha Synuclein Monoclonal Antibody Lu AF82422 for the Treatment of Patients with MSA: Results from the Phase 2 AMULET Trial
Objective: Assess the efficacy and safety of monthly IV infusions with the anti-alpha synuclein [a-syn] monoclonal antibody Lu AF82422 for the treatment of patients with…Posterior Fossa Arachnoid Cysts In Two Patients With Suspected Multiple System Atrophy – Cerebellar Type
Objective: To describe two patients with posterior fossa arachnoid cysts later diagnosed with suspected multiple system atrophy – cerebellar type (MSA-C). Background: The diagnosis of…18F-Florzolotau Positron Emission Tomography Imaging Correlates with Regional Brain Atrophy and Plasma Biomarkers in Tauopathy Parkinsonism Syndrome
Objective: We aim to investigate the relationship between regional 18F-florzolotau uptake and clinical severity, structural volume changes, and plasma markers in tauopathy parkinsonism syndrome. Background:…Diagnostic Spectrum in a Cohort of Atypical Atypical Parkinsonism
Objective: To retrospectively look at atypical Parkinsonism mimics in our cohort and reappraise the clinical features of these subset of patients Background: Atypical parkinsonism syndromes…Sex Differences for Regional Lewy Body Pathology in Pathologically-Defined Lewy Body Dementia
Objective: To investigate sex differences for regional Lewy body (LB) pathology burden, and regional LB pathology association with clinical diagnosis across people with a high…Accuracy of Clinical features for Substantia Nigra Hypopigmentation and Cortical Lewy Body Presence in the Oldest-Old: The 90+ Study
Objective: To improve clinical diagnostic accuracy of Lewy Body Dementia (LBD), we assessed if frontal release signs are a useful screening tool for cortical Lewy…Understanding Sleep-wake Disturbances in Dementia with Lewy Bodies Using Parametric and Non-parametric Measures in Wrist Actigraphy
Objective: To assess rest-activity and circadian rhythm stability in Dementia with Lewy bodies (DLB) and their relationship with cognitive, behavioural, and quality of life measures.…
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