Clinical characteristics and Brain atrophy pattern in the prospective multicenter cohort of Progressive Supranuclear Palsy
Objective: This study aims to investigate volumetric brain MRI features, clinical parameters and their correlations in the Study of Comprehensive ANd multimodal marker-based Cohort of…Metabolic Covariance Networks in Progressive Supranuclear Palsy Revealed by Spatial independent component analysis
Objective: The study aims to apply S-ICA to 18F-fluorodeoxyglucose (FDG) data in progressive supranuclear palsy (PSP) patients, identifing PSP-specific independent metabolic covariate networks. We also…Study of the functional role of circulating extracellular vesicles as mediators of inflammation in cellular models of Parkinson`s disease
Objective: To study mechanisms of cellular inflammation and neurodegeneration of EVs derived from patients with PD at different disease stages in cell-based disease models. Background:…Progression of motor asymmetry in the MDS-UPDRS III in Parkinson’s Disease with and without REM Sleep Behavior Disorder over five years
Objective: To compare progression of motor asymmetry using the MDS-UPDRS-III in Parkinson’s Disease (PD) with and without probable REM Sleep Behavior disorder (pRBD) over 5…Concordance of Neuropathologic Diagnosis of Lewy Body Disease with Baseline Alpha-Synuclein Seed Amplification Assay in PPMI
Objective: To determine whether the alpha-synuclein seed amplification assay (aSyn-SAA) performed on cerebral spinal fluid (CSF) collected at the baseline (BL) PPMI visit is concordant…A case of progressive supranuclear palsy followed by dementia with Lewy bodies
Objective: We report a case of dementia with Lewy bodies (DLB) that was diagnosed one year after the diagnosis of PSP. Background: Progressive supranuclear palsy…Real-world use of biomarkers for Parkinsonism: Should I do this (pSyn) or DaT?
Objective: To examine the utility of commercially available skin phosphorylated alpha-synuclein deposition test (pSyn) in patients with clinically ambiguous parkinsonism and its concordance with dopamine…The Challenges of Very Late-Onset Parkinson’s Disease: Perspectives from Patients, Primary Caregivers and Attending Physicians.
Objective: The purpose of this study is to investigate the difficulties faced by very late-onset patients with Parkinson’s disease (PD), caregivers and attending physicians, and…Giant Aneurysm Causing Parkinsonism and REM Sleep Disorder
Objective: To describe a stepwise evaluation of a patient with a secondary parkinsonism that mimic idiopathic Parkinson´s Disease (PD). Background: PD clinically established encompasses the…Eye movements and cognitive function
Objective: find out the relationship between eye movements and cognitive function (CF). Background: working in our clinic we have learned to give a pre-assessment of…
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