Targeted Brain Delivery of Rifampicin via PEG-PLA Nanoparticles: A Promising Therapeutic Strategy for Neuroprotection and Disease Modification in Parkinsonian Mouse Models
Objective: This study aimed to design and validate a nanoparticle-based delivery system for rifampicin, with the objective of enhancing its therapeutic efficacy, improving brain targeting,…Transformation of Parkinson’s care through Self-Management, Remote monitoring and Timely review (SMaRT-PD): Care Pathway Mapping with Clinical Experts
Objective: To elicit healthcare professionals’ perspectives on the introduction of a clinical decision support system (CDSS) to facilitate Parkinson’s disease care provision: impact on current…Stretegy of self-care in patient with Parkison disease: a metasynthesis
Objective: The purpose of this study is to synthesize the literature on self-care strategies implemented by patients with idiopathic Parkinson’s disease. Background: Parkinson’s disease presents…Audit Of A Multidisciplinary Day Hospital For Parkinson’s and Falls (2019–2024)
Objective: To assess a multidisciplinary hospital day service for Parkinson’s disease and fall-related concerns, identify service gaps, and evaluate its 5-year impact. Background: The Day…“Magic carpet for freezing of gait ” Evaluating a combination of patterned and pictographic visual cues.
Objective: To devise a portable skid free mat bearing a combination of patterned and pictographic visual cues for freezing of gait. Background: Freezing of gait…Incidence and Determinants of Nodule formation in continuous subcutaneous Foslevodopa/Foscarbidopa Infusion therapy.
Objective: This study aims to evaluate the incidence of subcutaneous (SC) nodules in Parkinson’s patients treated with continuous 24-hour SC infusion of foslevodopa/foscarbidopa (LDp/CDp) and…Modified Timed Up and Go test as a marker for motor improvement in advanced Parkinson’s disease after in-patient multimodal intensive neurorehabilitation and care
Objective: To determine if a modified Timed Up and Go (TUG) test can be used to monitor motor improvement in patients with Parkinson’s disease (PD)…IncobotulinumtoxinA to Treat Sialorrhea in Parkinson’s Disease: a Real-life Study: 6-year Interim Results
Objective: We evaluate the long-term efficacy and safety of incobotulinumtoxinA injections in advanced Parkinson’s disease (PD) patients suffering from sialorrhea. Background: Sialorrhea is frequently a…Longitudinal Remote Monitoring with Wearable Technology in Parkinson Disease: Initiation of A Dyskinesia Insight Network Observational Study
Objective: Evaluate the utility of wearable digital health technology for identifying and characterizing levodopa-induced dyskinesia in real-world settings. Background: Patients with Parkinson disease (PwP) frequently…Continuous Subcutaneous Apomorphine Infusion (CSAI) Reduces OFF Periods and Extends Periods of GOOD ON Time: Heatmap Analysis of the TOLEDO Study
Objective: Use heatmap analysis to quantify and examine diurnal patterns of OFF and GOOD ON time periods throughout the day, and changes in the number…
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