Parkinson’s Disease and Movement Disorders Mortality in Tunisia: Insights from the National Information System on Causes-of-Death (2020-2021)
Objective: Our study aimed to describe mortality related to Parkinson's disease (PD) and movement disorders in Tunisia during 2020-2021. Background: Parkinson's disease and related movement…Investigating the role of NLRP3 Inflammasome as Biomarkers and Therapeutic Targets in Parkinson’s Disease Pathogenesis
Objective: To elucidate the role of NLRP3 Inflammasome in PD pathogenesis and its role in differential susceptibility. Background: Inflammasomes play a role in the progression…The effect of vortioxetine and mirtazapine on levodopa-induced dyskinesia in a rat model of Parkinson’s disease
Objective: To investigate the effect of vortioxetine and mirtazapine on levodopa-induced dyskinesia (LID) in a rat model of Parkinson’s disease (PD), we analyzed abnormal involuntary movements (AIMs)…Predicting the Cognitive-Psychiatric Phenotype of Parkinson’s Disease
Objective: Predict PD patient’s clinical scores from brain activity. Inform on which assessments capture true changes in cortical dynamics caused by PD and explain those…The Role of α7 Nicotinic Acetylcholine Receptor in Mitochondrial Homeostasis and Neuroprotection
Objective: This study aims to explore the neuroprotective role of α7 nicotinic acetylcholine receptor (α7nAChR) in mitochondrial homeostasis and its potential as a therapeutic target…Boosting the LTP-like Plasticity Effect of Intermittent Theta-burst Stimulation with Gamma Transcranial Alternating Current Stimulation improves Bradykinesia in Parkinson’s Disease
Objective: We investigated whether transcranial alternating current stimulation (tACS) applied at the gamma frequency (γ) frequency on the primary motor cortex (M1) improves long-term potentiation…Decreased DTI-ALPS Indices and their Association with Clinical Features in Parkinson’s Disease
Objective: To investigate possible glymphatic dysfunction using diffusion tensor image along the perivascular space (DTI-ALPS) in patients with Parkinson’s disease and their relationship with clinical…Subthalamic nucleus DBS outcomes correlate with white matter tractography in Parkinson’s Disease
Objective: To assess whether advanced diffusion magnetic resonance imaging (dMRI) techniques help to understand the outcome of Deep brain stimulation (DBS) surgery on Unified Parkinson’s…Scans Without Evidence of Dopamine Deficiency (SWEDD) in Early-Onset Parkinson’s Disease: Comprehensive Clinical Analysis
Objective: Aim of this study is to comprehensively compare motor and non-motor symptoms of individuals with Early Onset Parkinson's Disease (EOPD) with dopamine deficiency to…Genetic Correlations Between Parkinson’s Disease and Circulating Metabolites
Objective: To use genome-wide association studies (GWASs) to identify genetic correlations between Parkinson’s disease (PD) and circulating metabolites. Background: Metabolomics is the study of small…
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