From Campotomy to MR-Guided Focused Ultrasound Pallidothalamic Tractotomy for Parkinson’s: A Systematic Review in the Context of a Phase III Study
Objective: To summarize and review efficacy and safety evidence of pallidothalamic tractotomy (PTT) using MR-guided focused ultrasound (MRgFUS). Background: Speigel and Wycis performed lesions in…Evaluation of Changes in Non-Motor Symptoms in Parkinson’s Disease Patients: A Twelve-Month Follow-Up After Bilateral Deep Brain Stimulation in the Subthalamic Nucleus
Objective: To determine changes in NMS in PD patients twelve months after undergoing DBS implantation in the STN at the Centro Médico Nacional Siglo XXI…The discrepancy between self-reported hyposmia and objective assessment by Sniffin’ sticks in high risk of synucleinopathies and healthy controls.
Objective: To study the discrepancy between self-reported hyposmia and the objective assessment of Sniffin’ sticks (identification subset, SS-16) in high risk of synucleinopathy and healthy…The Role of Diet in the Relationship Between Hyposmia and Constipation in Patients with Parkinson’s Disease
Objective: To assess the relationship between diet in the relationship between non-motor symptoms in Parkinson’s disease (PD). Background: While the etiology of PD is not…Exploring sexuality, intimacy and relationship changes in people with Parkinson’s Disease and their partners; What do they want to know and how can we help?
Objective: To explore the beliefs and attitudes of individuals with Parkinson’s Disease (PD) (and partners) regarding discussions about topics that include sexual function, intimacy and relationships. Secondary objectives…Progression of Motor & Non-motor symptoms of Parkinson’s Disease with Prior History of Head Trauma
Objective: We compared the progression of motor (M) and nonmotor (NM) symptoms in subjects with Parkinson’s Disease (PD) with pre-existing head trauma (HT), with or…Differentiated approach to treatment and diagnosis of Parkinson’s disease
Objective: The anatomical and physiological characteristics of tremor in patients with Parkinson’s disease and essential tremor at the same age significantly influence diagnostic approaches, differentiation…Resolution Dependence of Machine Learning for Differential Diagnosis of Parkinsonian Eye Movements
Objective: To establish the extent to which high temporal resolution is required to differentiate between parkinsonian disease states from eye movements. Background: Previous studies have…Multimodal and Agentic Simulated AI Patients for Bridging the gap in Parkinson Disease Education
Objective: To develop an AI training platform in PD counseling that utilizes real-time NLP processing, multimodal inputs/outputs, and adaptive reinforcement learning supported by immediate feedback…Advancing Hypomimia Assessment in Parkinson’s Disease by Integrating a Continuous Monitoring Device into Clinical Practice
Objective: We aim to establish a robust, continuous method for monitoring hypomimia in Parkinson’s disease (PD), bridging the gap between sporadic clinical evaluations and real-life…
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