Epidemiology of Parkinson’s Disease and Parkinsonism in Kazakhstan from 2015 to 2024 based on National Health Data
Objective: To evaluate the prevalence and dynamics of Parkinson’s disease and parkinsonian syndromes in the population of Kazakhstan from 2015 to 2024 using data from…Beyond Diagnosis: Putaminal ADC Hyperintensity and Infratentorial Signs Reflect Motor Severity in MSA
Objective: To clarify the clinical significance of neuroimaging markers in multiple system atrophy (MSA) by (1) examining concordance among putaminal MRI markers across sequences, (2)…When Muscles Relax but Symptoms Persist: A Case of Dysfunctional Sensory-Motor Cortical Integration in Botulinum Toxin-Resistant Blepharospasm
Objective: To present a case of blepharospasm (BSP) with objective response to serial botulinum toxin injections but persistent subjective symptoms, highlighting the role of sensory…MDS Guidance Framework for Electronic Clinical Outcome Assessments: Updating Practices for Validation and Implementation
Objective: To present the draft International Parkinson and Movement Disorder Society (MDS) guidance framework for validating, evaluating, and implementing electronic clinical outcome assessments (eCOAs). Background:…Effects of Personalized Visual and Auditory Cueing on Sit-to-Stand Biomechanics in Individuals with Parkinson’s disease: A Subgroup Analysis
Objective: To investigate the effects of personalized visual and auditory cueing combined with task-specific sit-to-stand training on movement kinematics, functional mobility, and psychosocial outcomes in…Pain relief beyond motor cortex modulation: clinical–neurophysiological dissociation after M1-tDCS in Parkinson’s disease
Objective: To analyze the correlation between changes in pain-related outcomes and neurophysiological cortical measures following transcranial direct current stimulation (tDCS) in Parkinson’s disease (PD). Background:…Prevalence and associated factors of sarcopenia among Thai patients with ambulatory Parkinson’s disease
Objective: Objectives: To determine the prevalence of Asian Working Group for Sarcopenia (AWGS) 2019-defined sarcopenia phenotypes, identify associated factors, and evaluate screening performance in Thai PD patients. Background: Sarcopenia is…Exploring the Relationship Between Circadian Disruption, Depression and Suicidal Ideation in People with Huntington’s Disease (Mind & Clock Study)
Objective: To examine the relationship between circadian and sleep disruptions and depressive symptoms and suicidal ideation in people with Huntington’s Disease (PwHD) using scale-based and…Adaptive Subthalamic Nucleus Deep Brain Stimulation (aDBS) for Refractory Dyskinesia in Parkinson’s Disease: A Case Report of Two Patients
Objective: This is a case report of two patients to using adaptive subthalamic nucleus deep brain stimulation (aDBS) for refractory dyskinesia Background: Although continuous subthalamic…Semiquantitative [¹²³I]FP-CIT SPECT metrics combined with machine learning improve clinical differentiation of parkinson’s disease and atypical parkinsonian syndrome
Objective: To evaluate the capacity of semiquantitative striatal [¹²³I]FP-CIT SPECT-derived metrics to improve the clinical differentiation of degenerative parkinsonism through an integrated machine learning model.…
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