Cholinergic Innervation and Cognitive Functioning in De Novo Parkinson’s Patients with GBA Variations
Objective: To explore the regional cholinergic innervation and clinical characteristics of de novo Parkinson’s disease (PD) patients carrying GBA variants. Background: The most common genetic…In-vivo cholinergic basal forebrain degeneration and cognition in Parkinson’s disease: imaging results from the COPPADIS study
Objective: To assess associations between multimodal neuroimaging measures of cholinergic basal forebrain (CBF) integrity and cognition in a well-characterized multicentric cohort of Parkinson’s disease (PD)…Decreased Regional Cholinergic Signaling in Parkinson’s Disease
Objective: To identify regions of decreased cholinergic signaling in Parkinson's disease (PD) participants relative to cognitively normal controls as measured by positron emission tomography imaging…Early cognitive impairment is associated with specific regional cholinergic denervation in Parkinson’s disease
Objective: To evaluate regional cholinergic correlates of cognitive impairment in newly diagnosed, treatment-naïve Parkinson’s disease (PD) patients. Background: Mild cognitive impairment (PD-MCI) is a common…Clinical and neurological features of the course of parkinsonism in the presence of chronic renal disease
Objective: To study the clinical and neurological features of the course of parkinsonism in chronic renal disease. Background: Under our supervision were 30 patients with…Donepezil for mild cognitive impairment in Parkinson’s disease: A 48-week follow-up study
Objective: To investigate the efficacy of donepezil for mild cognitive impairment (MCI) in Parkinson’s disease (PD). Background: MCI is common in PD. The mechanism of…Compared the effects of probiotics and Anti-PD particles on the behavior of Parkinson’s disease mice model
Objective: To compared the effects of probiotics and Anti-PD particles on the behavior of mice with MPTP Parkinson's disease (PD) model. Background: Intestinal flora may…Non-Invasive Vagus Nerve Stimulation: A non-pharmacological approach to target gait impairment in Parkinson’s disease?
Objective: To determine whether single dose non-invasive vagus nerve stimulation (nVNS) enhances gait performance in Parkinson’s (PD). Background: Loss of cholinergic neurons from nucleus basalis…Neuroprotective and neurotrophic efficacy of Ginkgo biloba extracts against 3-nitropropionic acid-induced oxidative stress in a rat model of Huntington’s disease
Objective: The present study examined the potential neuroprotective and neurotrophic efficacy of GBE against 3-nitropropionic acid (3-NP)-induced oxidative stress in a rat model of HD…Contribution of pedunculopontine nucleus cholinergic neurons to L-DOPA-induced dyskinesia and PD motor deficits in hemi-parkinsonian rats
Objective: To determine if chemogenetic and pharmacological modulation of pedunculopontine nucleus (PPN) cholinergic neurons can alter L-DOPA-induced dyskinesia and gait deficits in hemi-parkinsonian rats. Background:…
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