Semantic Memory Deficit as a Potential Risk Factor of Dementia in Isolated Rapid Eye Movement Sleep Behavior Disorder
Objective: We aimed to evaluate semantic memory (SM) performance in isolated/idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD) and identify the specific profile of…Diagnostic and Treatment Delays in Normal Pressure Hydrocephalus: A Retrospective Analysis at a Tertiary Care Center
Objective: To identify and evaluate critical points of delay in the diagnosis and treatment of normal pressure hydrocephalus (NPH) at a tertiary care center. Background:…Bidirectional Relationships Between Frailty and DNAm Age Acceleration and its Mediation Effects on Physical Disability and Mortality
Objective: This study aims to investigate the bidirectional associations between frailty and DNA methylation (DNAm) age acceleration (AgeAccel), and further test whether epigenetic aging mediates…Transformation of Parkinson’s care through Self-Management, Remote monitoring and Timely review (SMaRT-PD): Care Pathway Mapping with Clinical Experts
Objective: To elicit healthcare professionals’ perspectives on the introduction of a clinical decision support system (CDSS) to facilitate Parkinson’s disease care provision: impact on current…End-of-life care management in Parkinson’s disease: a national survey of caregivers’s own experiences and perceptions
Objective: To describe the personal experiences and perceptions of caregivers of people diagnosed with Parkinson's disease (PD) who are either in the advanced stages of…End-of-life care management in Parkinson’s disease: a nationwide survey of French healthcare practitioners’ experiences and perceptions
Objective: To describe the personal experiences and perceptions of healthcare practitioners (HCP) involved in the terminal management of people diagnosed with Parkinson's disease (PD) Background:…Artificial Intelligence for Understanding Parkinson Disease State and Patient Stratification Using CSF Proteomics
Objective: The objective of this research is to employ an Artificial Intelligence (AI) approaches to identify patient status and disease states in neurodegenerative diseases (NDDs),…Safety Profile of Opicapone in Elderly and Very Elderly Population
Objective: This study aimed to characterize the safety profile of opicapone (OPC) in the elderly and compare post-marketing safety between (A) very elderly patients (≥…Epigenome-wide and gene-targeted epigenetic profile of isolated REM Sleep Behaviour Disorder: a clinico-molecular study
Objective: Comprehensively characterize the epigenetic profile of isolated REM Sleep Behaviour Disorder (iRBD) using genome-wide and gene-targeted approaches, linking it to clinical measures and phenoconversion.…Role of APOE Polymorphism and CSF Markers of AD Co-Pathology in the Cognitive Trajectories of Sporadic and Genetic Parkinson’s Disease: A Longitudinal Cohort Study
Objective: To evaluate if APOE genotype and CSF biomarkers of AD co-pathology are associated with distinct rates of cognitive decline in PD subtypes. Background: Cognitive…
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