Scopolamine-induced Tardive Dyskinesia: A Case Report
Objective: To present a case of scopolamine-related Tardive Dyskinesia (TD) and review the documented anticholinergic-associated cases of TD and the underlying pathophysiology responsible for TD.…Trihexyphenidyl as a Treatment for Severe Freezing of Gait in Parkinson’s Disease: A Case Report
Objective: To present a unique case in which trihexyphenidyl was used as an effective treatment to dramatically reduce freezing of gait (FoG) in a Parkinson’s…Association between cognitive adverse effects of anticholinergic medication and development of long-term dementia in Parkinson’s disease
Objective: To investigate whether cognitive adverse effects occurring immediately after taking anticholinergics are related to the development of long-term dementia and to interpret this from…Trihexyphenidyl Use in a Parkinsonian Phenotype of Gerstman-Sträussler-Scheinker Syndrome
Objective: To highlight clinical improvement in a patient with a parkinsonian presentation of Gerstmann-Sträussler-Scheinker (GSS) syndrome who was treated with trihexyphenidyl. Background: GSS is a…Potentially inappropriate medication useage among patients newly diagnosed with dementia with Lewy bodies
Objective: Investigate the use of potentially inappropriate medications (PIM) among patients newly diagnosed with dementia with Lewy bodies (DLB). Background: PIM, including anticholinergics, are associated…Association Between Anticholinergic Burden, MCI, and Cholinergic Denervation
Objective: To characterize the relationship between anticholinergic burden (ACB), mild cognitive impairment (MCI), and its underlying cholinergic pathology. Background: MCI is a common phenomenon in…Changes in anticholinergic burden in patients with Parkinson’s disease (PD) after bilateral deep brain stimulation (DBS) of the globus pallidus (GP) and subthalamic nucleus (STN)
Objective: To evaluate the effect of GP and STN DBS upon anticholinergic medication burden in patients with PD. Background: Medications with anticholinergic effects are commonly…Hyperkinetic movement disorder following Covid: A Temporal corelation or Coincidental ?
Objective: Hypokinetic movement disorder and parkinsonian like picture has been well described in literature but hyperkinetic movements are extremely rare and less highlighted in global…Adult-onset axial dystonia: a rare condition that can lean on an early combined treatment approach
Objective: To describe a rare case of adult-onset axial dystonia treated successfully with a combined therapeutic approach. Background: Adult-onset truncal dystonia is an unusual condition…Low dose trihexyphenidyl use causes cognitive dysfunction in Parkinson’s disease patients.
Objective: Evaluate cognitive performance in Parkinson's disease patients receiving a low dose of trihexyphenidyl (THP). Background: Before L-Dopa's discovery, anticholinergic drugs were among the first…
