Apathy Following Bilateral Subthalamic Deep Brain Stimulation for Parkinson’s Disease: The INTREPID Randomized Controlled Trial
Objective: To determine frequency and predictors of improvement or worsening of apathy in participants receiving bilateral subthalamic deep brain stimulation (STN-DBS) for the treatment of…Dissociated longitudinal evolution of limbic serotonergic and striatal dopaminergic and serotonergic pathology in apathetic and non-apathetic patients in early Parkinson’s disease
Objective: To investigate the longitudinal changes in striatal and extra-striatal dopaminergic and serotonergic innervation in apathetic and non-apathetic patients during the five years after the…Evaluating the Relationship between Apathy and Grit as it Relates to Participation in a Community Exercise Program in the Population with Parkinson’s Disease.
Objective: The primary aim of this study was to explore the relationship between apathy levels of the PD individual and apathy levels of their caregiver.…Influence of emotion-affective apathy in theory of mind in Parkinson’s disease patients
Objective: The study aimed to investigate apathy subdomains (reward deficiency syndrome, emotional distress, executive function, auto-activation deficit) and cognitive executive functions differences between PD patients…Comparison of gait pattern characteristics during Parkinson’s disease progression – Analysis of gait during the dual-task walking
Objective: We investigated gait characteristics and contribution of clinical presentation and cognitive functioning to the gait characteristics in different Parkinson’s disease (PD) stages. Our aim…The relationship between neuromelanin-sensitive MRI, [123I] meta-iodobenzylguanidine scintigraphy and cognition, in patients with Parkinson’s disease
Objective: We investigate the relationship between the contrast ratio of locus coeruleus (LC-CR) in neuromelanin-sensitive MRI(NMI), MIBG scintigraphy, and cognition/hallucination, in patients with Parkinson’s disease.…Prevalence of apathy in Indian patients with Parkinson’s disease and its correlation with nigrosomal imaging
Objective: To assess the prevalence of apathy in patients with patients with Parkinson's disease and to correlate it with nigrosomal imaging in a subset of…Pet ownership associated with lower apathy and motor severity in female participants with PD
Objective: This study evaluated the impact of pet ownership on Parkinson’s disease (PD) severity and related symptoms. Background: PD is a common neurodegenerative disease characterized…Apathy as a non-motor symptom(NMS) in patients with Parkinson’s disease(PwPD) and patients with Huntington’s disease(PwHD) in Tomsk, Russia
Objective: The aim is to evaluate and compare the apathy profile in PwHD and PwPD, using the same clinical criteria to assess the severity of…MOve To ImprovE physical activity in Parkinson’s disease (MOTIvatE): A pilot randomized clinical trial of gamification
Objective: To test the feasibility and impact of a behaviorally designed gamification intervention to improve goal-directed behavior assessed by physical activity levels in Parkinson’s disease…
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