MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Ataxia: Treatment"

  • 2018 International Congress

    Dissociative effects of thyrotropin releasing hormone on classical cerebellar ataxic signs and cerebellar adaptation in patients with spinocerebellar degeneration

    T. Shimizu, R. Hanajima, R. Tsutsumi, N. Tominaga, Y. Ugawa, K. Nishiyama (Sagamihara, Japan)

    Objective: To reveal effects of TRH [Thyrotropin releasing hormone (protirelin tartrate)] on the prism adaptation task in patients with spinocerebellar degeneration (SCD). Background: The cerebellum…
  • 2018 International Congress

    Treatment with docosahexaenoic acid in Spinocerebellar Ataxia 38

    D. Perani, L. Orsi, C. Costanzi, M. Ferrero, A. Zoppo, F. Tempia, D. Caruso, M. Grassi, A. Padovani, A. Brusco, B. Borroni (Brescia, Italy)

    Objective: To evaluate the safety and efficacy of docosahexaenoic acid supplementation in patients with spinocerebellar ataxia 38 (SCA 38), on clinical symptoms and changes of…
  • 2017 International Congress

    Targeting the intracellular localization of Ataxin-3 as novel treatment strategy for Spinocerebellar Ataxia Type 3

    T. Schmidt, Z. Wang, A. Sowa, J. Schmidt, M. Anders, M.I. Martins, A. de Castro, D. Weishäupl, J. Weber, H. Tricoire, P. Maciel, O. Riess (Tuebingen, Germany)

    Objective: Spinocerebellar ataxia type 3 (SCA3) or Machado-Joseph disease (MJD) is an autosomal-dominantly inherited neurodegenerative disorder caused by a CAG expansion in the ATXN3 gene…
  • 2017 International Congress

    Is the cerebellum a good target for neuromodulation in movement disorders?

    C. França, M. Teixeira, D. de Andrade, R. Galhardoni, V. Barbosa, V. Silva, G. Lepski, E. Barbosa, R. Cury (São Paulo, Brazil)

    Objective: To assess the effects of dentate nucleus transcranial magnetic stimulation and deep brain stimulation on patients with cerebellar ataxia of different etiologies. Background: Cerebellar…
  • 2017 International Congress

    Effectiveness of Deep Brain Stimulation (DBS) in Mice with Spinocerebellar Ataxia (SCA1).

    V. Vedam-Mai, K. McFarland, R. Nathu, S. Kurtovic, Q. Zhang, T. Ashizawa, M. Okun (Gainesville, FL, USA)

    Objective: To evaluate the effectiveness of Deep Brain Stimulation (DBS) in a mouse model of Spinocerebellar Ataxia type 1 (SCA1). Background: Spinocerebellar ataxia type 1…
  • 2016 International Congress

    Evaluating the effects of deep brain stimulation (DBS) in mice with spinocerebellar ataxia (SCA1)

    V. Vedam-Mai, K. McFarland, Q. Zhang, H. Kim, R. Nathu, S. Kurtovic, K. Savery, T. Ashizawa, M.S. Okun (Gainesville, FL, USA)

    Objective: To determine the therapeutic effects of Deep Brain Stimulation (DBS) in mice with Spinocerebellar Ataxia (SCA1). Background: Ataxia is a movement disorder affecting balance…
  • 2016 International Congress

    European pediatric normative values for the scale for assessment and rating of ataxia (SARA)

    T.F. Lawerman, R. Brandsma, R.J. Lunsing, J.G.M. Burgerhof, D.A. Sival, On behalf of the Childhood Ataxia and Cerebellar Study Group of the European Pediatric Neurology Society, N. Barisic, P. Baxter, E. Bertini, L. Blumkin, V. Brankovic, G.E. Calabro, C.E. Catsman-Berrevoets, D. Craiu, B. Dan, A. Dica, T. Franciskovic, J. Gburek-Augustat, S. Grunt, H. Hartley, F. Kammoun, C. Kennedy, M.J. Kuiper, I. Lehman, A. Lustenberger, F. Mancini, M. Mirabelli-Badenier, E. Mulder-den Hartog, M. Steinlin, M. Synofzik, C.C. Triki, E.M. Valente, G. Vasco, A. Zekavica (Groningen, Netherlands)

    Objective: To obtain international age-related normative values for the SARA in healthy European children. Background: The Scale for Assessment and Rating of Ataxia (SARA) is…
  • 2016 International Congress

    The nucleocytoplasmic transport of ataxin-3 as pathogenic mechanism in spinocerebellar ataxia type 3

    T. Schmidt, A. Sowa, I.M. Martins, M. Abedi, Z. Wang, J. Schmidt, H. Tricoire, O. Riess (Tübingen, Germany)

    Objective: Spinocerebellar ataxia type 3 (SCA3) or Machado-Joseph disease (MJD) is a neurodegenerative disorder caused by a CAG expansion in the MJD1 gene leading to…
  • 2016 International Congress

    Clinical benefits of vestibular rehabilitation in neurodegenerative diseases

    B.S. Zeigelboim, G.B. Santos, H.A.G. Teive, M.I.R. Severiano, C.M. Porto (Curitiba, Brazil)

    Objective: To assess the benefits of vestibular rehabilitation using virtual reality technology through pre and post application of the Dizziness Handicap Inventory (DHI) and the…
  • 2016 International Congress

    Deep brain stimulation of the dentate nucleus improves ataxia and modulates cortical excitability

    C.C. França, M.J. Teixeira, D. Ciampi de Andrade, R. Galhardoni, V.R. Barboza, V. Silva, G. Lepski, E.R. Barbosa, R.G. Cury (São Paulo, Brazil)

    Objective: To assess tremor and ataxia changes by dentate nucleus deep brain stimulation and evaluate how DBS could modulate cortical excitability seen in cerebellar stroke.…
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