Feature Extraction and Classification Using Smartphone-Based Alternating Tapping Tasks for Distinguishing Parkinson’s Disease from Healthy Individuals
Objective: To determine whether a smartphone-based alternating tapping task can reliably differentiate Parkinson’s disease (PD) from healthy controls and to identify the tapping metrics that…Quantitative assessment of micrographia and bradykinesia in Parkinson’s disease
Objective: We aimed to evaluate if micrographia in Parkinson’s disease (PD) patients correlates with the severity of bradykinesia and whether or not micrographia is improved…Promising Remote Markers of Motor Progression in Isolated REM Sleep Behaviour Disorder
Objective: To define the motor progression of motor prodromes using two remote keyboard tapping tests (BRAIN and DFT tests) and two remote standardised clinical rating…Exploring minzasolmin effect on digital measures captured by the Verily Study Watch in a subset of the ORCHESTRA trial participants
Objective: To investigate the progression over time and the effect of minzasolmin on digital outcomes collected in ORCHESTRA (NCT04658186). Background: Minzasolmin is an oral small…Differentiated approach to treatment and diagnosis of Parkinson’s disease.
Objective: The anatomical and physiological characteristics of tremor in patients with Parkinson’s disease and essential tremor at the same age significantly influence diagnostic approaches, differentiation…Adaptive Deep Brain Stimulation Algorithmic Performance Evaluation Through Symptom Driven Metrics
Objective: To develop a standardized scoring system design to systematically assess and monitor adaptive algorithm performance over time in Parkinson’s disease (PD) patients. Background: Deep…Redefining the Finger-tapping Test in Parkinsonian Patients: Finger to Crease Instead of Finger-to-tip
Objective: To evaluate the competence of finger to crease (F-C) variation of the finger tapping test as opposed to the traditional method (F-T) in detecting…Young-onset Parkinson’s disease in a female with pathogenic deletion of the PRRT2 gene
Objective: To report a novel case of young-onset Parksinon’s disease (YOPD) associated with a pathogenic deletion of the proline-rich transmembrane protein 2 gene (PRRT2). Background:…Adding Parkinsonism to the Phenotypic Spectrum of FIG4-related diseases
Objective: To describe a phenotypic variant of FIG4-related diseases resulting in parkinsonism. Background: The FIG4 gene codes for P1(3,5)P2 phosphatase that plays an important role…Deep brain stimulation-evoked potentials as an avenue to optimize stimulation outcomes in Parkinson’s disease
Objective: Use deep brain stimulation (DBS)-evoked potentials recorded using dry-EEG electrodes to estimate stimulation outcome. Background: Subthalamic DBS effectively alleviates motor symptoms in Parkinson’s disease.…
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