Effectiveness of deep brain stimulation in the treatment of Huntington’s disease
Objective: The aim is to obtain relevant information regarding the effectiveness of using Deep Brain Stimulation (DBS) as a treatment of Huntington's disease (HD). Background:…Crushing valbenazine capsule contents for potential addition to soft foods or administration via G tube
Objective: To evaluate the suitability of mixing crushed contents from valbenazine capsules with soft foods/liquids or adding them to water for delivery through a gastrostomy…Chorea improvements over time with once-daily valbenazine treatment in adults with Huntington disease
Objective: To describe the effects of valbenazine (VBZ) over time on chorea in adults with Huntington disease (HD). Background: The Ph3 KINECTTM-HD (NCT04102579) trial met…Baseline Characteristics and Treatment Patterns of a Global Huntington Disease Population Stratified by Chorea Severity
Objective: To describe baseline characteristics and treatment patterns in patients with chorea associated with Huntington disease (HD) by severity of chorea. Background: Though multiple treatment…4 YEARLONG POST PARTUM AUTOIMMUNE CHOREA AS INITIAL PRESENTATION OF INCOMPLETE SLE/APS
Objective: The aim is to report a case of a 4 yearlong postpartum autoimmune chorea secondary to incomplete SLE/APS. Background: Chorea is a movement disorder…Real-World Treatment Patterns and Outcomes in Patients With Chorea Associated With Huntington Disease Using Tetrabenazine or Deutetrabenazine in Combination with Antipsychotic Drugs
Objective: To describe treatment patterns with vesicular monoamine transporter 2 inhibitors (VMAT2i; tetrabenazine [TBZ], or deutetrabenazine [DTBZ]) in combination with antipsychotic agents (APs) in patients…Clinical and biomarker characteristics of Huntington’s Disease patients recently proposed for huntingtin-lowering clinical trial inclusion
Objective: We investigated plasma NfL levels, as well as clinical measures, in Huntingtin (Htt)-mutation carriers 48 years of age and under, with a CAP score…The START Study: A Phase 4 Study on the Real-World Utilization of Deutetrabenazine Initiated by a 4-Week Patient Titration Kit
Objective: To assess the real-world utilization of deutetrabenazine (DTBZ) for the treatment of tardive dyskinesia (TD) or chorea associated with Huntington disease (HD) initiated by…Contemporary study of the difficulties of late diagnostics in patients with Huntington’s disease in Uzbekistan
Objective: To identify the causes that lead to late diagnosis of Huntington's disease. Background: Huntington's disease is a rare, progressive, and fatal autosomal dominant neurodegenerative…A randomized, sham-controlled, crossover trial on Transcranial pulsed current stimulation (tPCS) in Huntington disease
Objective: 1. To assess brain network level dysfunction of Huntington disease (HD). 2. To evaluate the effectiveness of 2-week home-based chronic non-invasive transcranial brain stimulation (NIBS) in…
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