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Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Chorea (also see specific diagnoses, Huntingtons disease, etc): Treatment"

  • 2022 International Congress

    Long-term Deutetrabenazine Safety on Motor, Psychiatric, and Cognitive Measures in Individuals With Chorea Associated With Huntington Disease

    M. Gordon, D. Stamler, J. Savola, N. Gross, H. Barkay, M. Chen, N. Chaijale (West Chester, USA)

    Objective: To evaluate long-term deutetrabenazine safety on motor, psychiatric, and cognitive measures in participants with chorea associated with Huntington disease (HD). Background: Deutetrabenazine, a vesicular…
  • 2022 International Congress

    Baseline Characteristics and Treatment Patterns of a Global Huntington Disease Population Stratified by Chorea Severity

    V. Sung, E. Furr Stimming, S. Reshef, R. Willock, R. Ribalov, S. Brighton, S. Leo (Birmingham, USA)

    Objective: To describe baseline characteristics and treatment patterns in patients with chorea associated with Huntington disease (HD) by severity of chorea. Background: Though multiple treatment…
  • 2022 International Congress

    4 YEARLONG POST PARTUM AUTOIMMUNE CHOREA AS INITIAL PRESENTATION OF INCOMPLETE SLE/APS

    W. Trillo Alvarez, J. Medina Suárez, J. Molina Acosta, A. Escalante Mercado, C. Ibañez Escalante, E. Carrillo Monteagudo, V. Medina Cerpa, E. Ramos Luza, P. Gonzales Romero, G. García Huamán (AREQUIPA, Peru)

    Objective: The aim is to report a case of a 4 yearlong postpartum autoimmune chorea secondary to incomplete SLE/APS. Background: Chorea is a movement disorder…
  • 2022 International Congress

    Real-World Treatment Patterns and Outcomes in Patients With Chorea Associated With Huntington Disease Using Tetrabenazine or Deutetrabenazine in Combination with Antipsychotic Drugs

    D. Claassen, H. Romdhani, R. Ayyagari, D. Goldschmidt, S. Zoye Moroz, A. Hernandez, S. Leo (Nashville, USA)

    Objective: To describe treatment patterns with vesicular monoamine transporter 2 inhibitors (VMAT2i; tetrabenazine [TBZ], or deutetrabenazine [DTBZ]) in combination with antipsychotic agents (APs) in patients…
  • MDS Virtual Congress 2021

    Reversible hemichorea due to contralateral anterior cerebral artery territory hypoperfusion

    S. Adukia, P. Shah, M. Shrivastava, G. Sangani, D. Sanghvi, M. Bhatt, A. Aggarwal (Mumbai, India)

    Objective: We report hemichorea due to hypoperfusion of the contralateral anterior cerebral artery (ACA) territory (including caudate nucleus and its connections) that reversed with revascularization.…
  • MDS Virtual Congress 2021

    Medically refractory Graves’ disease presenting as chorea and carbohydrate hyperphagia in a Kenyan adolescent

    N. Mongare, E. Njenga, D. Sokhi (Nairobi, Kenya)

    Objective: To report a unique case of adolescent-onset autoimmune hyperthyroidism presenting with chorea and carbohydrate hyperphagia (CH). Background: Autoimmune hyperthyroidism [Graves’ disease (GD)] can cause…
  • MDS Virtual Congress 2021

    Predictors of Persistence to Deutetrabenazine Among Patients With Tardive Dyskinesia (TD) and Huntington’s Disease (HD)

    D. Claassen, R. Ayyagari, V. Garcia-Horton, S. Zhang, S. Leo (Nashville, USA)

    Objective: To identify real-world predictors of persistence to deutetrabenazine in patients with TD or HD. Background: Deutetrabenazine is FDA-approved to treat TD in adults and…
  • MDS Virtual Congress 2021

    Evaluation of the QTc prolongation risk of deutetrabenazine

    F. Schneider, B. Darpo, M. Gutierrez, M. Gordon, L. Rabinovich-Guilatt (Ulm, Germany)

    Objective: To assess QTc prolongation risk of deutetrabenazine and its active metabolites by conducting exposure-QTc interval modeling, and to predict QTc prolongation in both CYP2D6…
  • MDS Virtual Congress 2021

    Proof-of-concept study testing bevantolol (SOM3355) as treatment of chorea in Huntington’s disease

    J. Gamez, M. Calopa, E. Muñoz, A. Ferré, O. Huertas, K. Mcallister, N. Reig, C. Scart-Grès, R. Insa, J. Kulisevsky (Barcelona, Spain)

    Objective: Proof-of-concept phase IIa study assessing bevantolol (SOM3355) efficacy and safety in reducing chorea in Huntington’s disease (HD). Background: Bevantolol hydrochloride, a β1‐adrenoceptor antagonist used…
  • MDS Virtual Congress 2021

    Diabetes Mellitus in Huntington’s disease. The Argentinean perspective

    N. Gonzalez Rojas, M. Cesarini, J. Etcheverry, E. Gatto (Buenos Aires, Argentina)

    Objective: to compare the prevalence of diabetes mellitus (DM) in a self-reported series of local Huntington disease (HD) participants in the ENROLL-HD registry with the…
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