Striatal dopamine transporter availability changes reflect gastrointestinal dysautonomia severity in early Parkinson’s disease
Objective: To test the hypothesis that constipation and gastrointestinal (GI) dysautonomia may be correlated with nigrostriatal dopaminergic (DA) dysfunction in PD. Background: Constipation is a…Early gastrointestinal dysfunction is predictive of faster progression in Parkinson’s disease
Objective: To evaluate whether constipation at time of diagnosis has prognostic significance in terms of motor and cognitive progression in PD. Background: There is evidence…Pain is correlated with other motor and non-motor symptom in Parkinson’s disease
Objective: Study pain occurrence and appearance in Parkinson’s disease (PD), and its relationship with other motor and non-motor symptoms like constipation and footsteps. Background: The…Gut microbiota geography in Parkinson’s disease in the world
Objective: The 16 rRNA analysis and the shotgun metagenome analysis in our cohort were compared with 5 previous reports by others. Background: In PD patients,…Objective intestinal dysfunction in REM sleep behaviour disorder
Objective: To study objectively measured intestinal function, defined by intestinal volume, transit times, and colonic motility patterns in patients with idiopathic REM sleep behaviour disorder…Alteration of the fecal microbiota in Chinese patients with Parkinson’s disease
Objective: Emerging evidences suggest that gut microbiota dysbiosis plays a role in Parkinson’s disease (PD). However, the alterations in fecal microbiome in Chinese PD patients…A randomized double-blind placebo-controlled trial of probiotics for constipation in Parkinson’s disease
Objective: To investigate the effects of probiotics on constipation in PD, using a randomized controlled trial (RCT) design Background: Non-motor symptoms (NMS) cause significant disability…Helicobacter pylori eradication and risk of Parkinson’s disease in patients with peptic ulcers
Objective: To observe the effect of Helicobacter pylori eradication on the incidence of Parkinson's disease Background: The prevalence of Helicobacter pylori (H. pylori) is high in Parkinson's disease (PD)…Associations of probable REM sleep behavior disorder, constipation, and hyposmia with PD
Objective: To estimate the relative risk of PD according to combinations of prodromal features. Background: Clinical PD is preceded by a prodromal period characterized by…Diagnosis of Irritable Bowel Syndrome Increases Risk of Parkinson’s Disease in the Finnish Population
Objective: To assess risk of Parkinson’s disease in patients with irritable bowel syndrome in the Finnish population. Background: The majority of Parkinson’s disease (PD) patients…
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