MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Dementia with Lewy bodies (DLB)"

  • 2025 International Congress

    The Syn-D Study: Detection of Cutaneous Phosphorylated Alpha-Synuclein and blood P-Tau 217 in Patients with Mild Cognitive Impairment

    C. Gibbons, T. Levine, B. Bellaire, R. Freeman (Boston, USA)

    Objective: To quantify the deposition of cutaneous P-SYN and blood P-Tau 217 in patients with suspected DLB and AD at the mild cognitive impairment (MCI)…
  • 2025 International Congress

    Plasma Biomarkers Predict Clinical Outcomes in Individuals with Neuronal α-Synuclein Disease and Amyloid-β Co-Pathology

    S. Lorkiewicz, C. Abdelnour, A. Smith, N. Siddiqui, L. Montoliu-Gaya, E. Wilson, N. Ashton, B. Arslan, M. Plastini, C. Young, J. Winer, M. Shahid-Besanti, H. Vossler, V. Ramirez, G. Kerchner, K. Andreasson, V. Henderson, T. Montine, L. Tian, E. Mormino, H. Zetterberg, K. Poston (Gothenburg, Sweden)

    Objective: We examined whether the plasma biomarkers pTau181, pTau217, GFAP, NfL, and Aβ42/40 are associated with cognitive, functional, and motor outcomes in individuals with neuronal…
  • 2025 International Congress

    A Longitudinal Quantitative Assessment of Phosphorylated Alpha-Synuclein Deposition in Dementia with Lewy Bodies

    C. Gibbons, T. Levine, B. Bellaire, R. Freeman (boston, USA)

    Objective: To report the quantitative change in cutaneous phosphorylated alpha-synuclein (P-SYN) deposition over time in patients with dementia with Lewy bodies (DLB) in a longitudinal…
  • 2025 International Congress

    Cognitive and Motor Wobbling in Isolated RBD: A Multicentric Study by the International RBD Study Group (IRBDSG)

    A. Stefani, S. Joza, D. Arnaldi, L. Baldelli, G. Benbir, B. Boeve, V. de Cock, L. Churchill, B. Högl, M. Hu, B. Huang, R. Kim, K. Kufer, J-Y. Lee, C. Liguori, B. Mollenhauer, L. Muntean, N. Li, B. Orso, M. Patyjewicz, R. Postuma, F. Provini, S. Lewis, C. Simonet, M. Sommerauer, A. Videnovic, Y. Wing, C. Trenkwalder (Innsbruck, Austria)

    Objective: To define and characterize clinically fluctuating transition phases from isolated RBD (iRBD) to overt alpha-synucleinopathy. Background: Patients with iRBD often develop motor and non-motor…
  • 2025 International Congress

    Patterns and Predictors of Cholinesterase Inhibitor Use in Dementia with Lewy Bodies

    R. Heo, A. Negida, K. Wyman-Chick, J. Bateman, F. Rodriguez-Porcel, B. Berman, N. Mukhopadhyay, M. Barrett (Richmond, USA)

    Objective: The objective of this study was to identify the patterns and predictors of cholinesterase inhibitor (ChEI) prescribing in Dementia with Lewy bodies (DLB) patients.…
  • 2025 International Congress

    Stratification study of alpha-synucleinopathy by body fluid biomarkers

    R. Kamo, A. Okuzumi, M. Iseki, T. Hatano, N. Hattori (Tokyo, Japan)

    Objective: This study aims to stratify patients with Parkinson's disease (PD) based on clinical features and several disease-associated biomarkers by analyzing the relationship between biomarkers,…
  • 2025 International Congress

    Development of the Lewy Body Dementia Domain Rating Scale (LBD-DRS): A disease-specific outcome measure

    E. Matar, B. Boeve, J. Kane, F. Rodriguez-Porcel, A. Schrag, S. Sikkes, J. Taylor (New South Wales, Australia)

    Objective: To develop and refine the Lewy Body Dementia Domain Rating Scale (LBD-DRS) as a disease-specific outcome measure tailored to the unique clinical features of…
  • 2025 International Congress

    Neural Signatures of Hallucination Emergence in Dementia with Lewy Bodies

    R. Vin, S. Moret, HY. Yi, M. Lawrence, V. Santini, J. Cedarbaum, A. Powers, C. Fredericks (New Haven, USA)

    Objective: REM sleep behavior disorder (RBD) is a prodromal state for alpha-synucleinopathy. Here, we present a behavioral marker for hallucination propensity that distinguishes Dementia with…
  • 2025 International Congress

    Advancing LBD Diagnosis: EEG Biomarkers for Cognitive Fluctuations

    H. Mayo, A. Negida, M. Ahsan, S. Lageman, N. Mukhopadhyay, M. Barrett (Richmond, USA)

    Objective: The objective of the study was to identify EEG features associated with cognitive fluctuations in patients with Lewy body dementia (LBD). Background: Cognitive fluctuations…
  • 2025 International Congress

    Immune cell changes in early Dementia with Lewy Bodies

    T. Yacoubian, H. Qin, A. Amara, N. Stover, L. Ruffrage, M. Dean, Y. Zhang, R. Kennedy, D. Geldmacher, A. Gerstenecker, D. Standaert, E. Benveniste (AURORA, USA)

    Objective: To examine if immune cell changes are present in early stages of Dementia with Lewy Bodies (DLB). Background: Evidence for inflammation in synucleinopathies has…
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