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Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Dementia"

  • MDS Virtual Congress 2021

    Genetic factors associated with dementia in Parkinson’s disease in the Parkinson’s Incidence Cohorts Collaboration (PICC)

    A. Szwedo, I. Dalen, M. Camacho, R. Lawson, D. Bäckström, L. Forsgren, C. Tzoulis, OB. Tysnes, A. Macleod, C. Counsell, C. Williams-Gray, KF. Pedersen, G. Alves, J. Maple-Grødem (Stavanger, Norway)

    Objective: To evaluate the effect of genetic variants in β-glucocerebrosidase (GBA), apolipoprotein E (APOE), microtubule-associated protein tau (MAPT), and α-synuclein (SNCA) loci on the risk…
  • MDS Virtual Congress 2021

    Methods for addressing missing covariate data in left truncated samples with application to Parkinson’s disease research

    H. Richardson, S. Xie (Philadelphia, USA)

    Objective: To investigate the impact of left truncation on commonly used missing data approaches and explore this impact in a Parkinson’s disease dementia study. Background:…
  • MDS Virtual Congress 2021

    CSF MicroRNA Analysis Reveals Angiogenesis And Autophagy Defects In Parkinson’s DiseasePatients

    C. Moussa, Y. Torres-Yaghi, F. Pagan (Washington, USA)

    Objective: We investigated the effects of discoidin domain receptor (DDR)-1 inhibition on CSF miRNAs in Parkinson’s disease patients. Background: MicroRNAs (miRNAs) are post-transcriptional regulators of…
  • MDS Virtual Congress 2021

    Therapy to Reduce dementia risk In Parkinson’s disease (TRIP): Proof-of-concept trial

    D. Pourzinal, A. Bakker, G. Byrne, K. Mcmahon, J. O'Sullivan, R. Adam, A. Lehn, D. Copland, J. Yang, G. Pontone, T. Au, R. Littleford, M. Chatfield, Z. Mari, N. Dissanayaka (Herston, Australia)

    Objective: The TRIP proof-of-concept study examines functioning of the hippocampal DG/CA3 subregion as a biomarker and therapeutic target for memory impairment in Parkinson’s Disease (PD).…
  • MDS Virtual Congress 2021

    Distinct memory networks in Parkinson’s disease (PD) and Alzheimer’s disease (AD): Effects of APOE

    G. Coughlan, P. Mclaughlin, K. Sunderland, M. Borrie, C. Fischer, A. Frank, M. Freedman, S. Kumar, S. Pasternak, B. Pollock, T. Rajji, D. Seitz, D. Tang-Wai, C. Tartaglia, J. Dewar, D. Kwan, B. Tan, D. Grimes, M. Jog, T. Lang, C. Marras, T. Steeves, D. Bulman, A. Dilliott, M. Ghani, R. Hegele, J. Robinson, E. Rogaeva, S. Farhan, R. Bartha, N. Nanayakkara, J. Ramirez, C. Scott, S. Symons, C. Berezuk, M. Holmes, S. Adamo, M. Ozzoude, A. Theyers, S. Arnott, D. Beaton, W. Lou, S. Sujanthan, B. Levine, J. Orange, A. Peltsch, A. Roberts, A. Troyer, M. Binns, S. Black, S. Strother, M. Moscovitch, C. Grady, M. Masellis (Toronto, Canada)

    Objective: As part of the Ontario Neurodegenerative Disease Research Initiative, we investigated group differences in functional connectivity within two distinct memory networks: posterior medial network…
  • MDS Virtual Congress 2021

    Exploring the Potential Anti-dementia Roles of Selected Herbal Anti-inflammatory Remedies in Parkinson’s Disease: Hopes and Challenges

    SA. Atunwa (Ilorin, Nigeria)

    Objective: To evaluate anti-dementia properties of the selected herbal anti-inflammatory remedies Background: Parkinson’s disease (PD) is the most common age-related neurodegenerative disease after Alzheimer’s disease.…
  • MDS Virtual Congress 2021

    The Neuropsychiatric Inventory:Assessment Of Neuropsychiatric Symptoms In Parkinson’s Disease

    GG. Uygun, GA. Yuksel, S. Kose (Istanbul, Turkey)

    Objective: We investigated the correlation of Neuropsychiatric Inventory(NPI) test score with progression of PD. Background: PD has characteristic motor symptoms and non-motor symptoms including psychiatric…
  • MDS Virtual Congress 2021

    Parkinsonism in a patient with limbic-predominant age-related TDP-43 encephalopathy (LATE) syndrome

    C. Selvadurai, S. Schaefer (New Haven, USA)

    Objective: To illustrate a case of parkinsonism in a patient with LATE syndrome. Background: LATE syndrome is an emerging subclassification of TDP-43 proteinopathy. Symptoms include…
  • MDS Virtual Congress 2021

    Progressive Gait Disturbance presumed to be caused by idiopathic peripheral neuropathy: A case of Normal Pressure hydrocephalus.

    K. Dalton, N. Hack (Bethesda, USA)

    Objective: Discuss the importance of gait phenomenology in identifying Normal Pressure Hydrocephalus. Background: Normal pressure hydrocephalus (iNPH) can present as a ‘magnetic gait’ but this…
  • MDS Virtual Congress 2021

    Sex-Specific APOE ε4 Association with Cognition in Lewy Body Dementia

    E. Bayram, S. Scholz, I. Litvan (La Jolla, USA)

    Objective: To evaluate whether association between apolipoprotein E ε4 (APOE ε4) and cognition differ for men and women with pathologically-confirmed Lewy body dementia (LBD). Background:…
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