Predictors of cognitive deficits in patients with idiopathic normal pressure hydrocephalus – a pilot MRI volumetric study
Objective: The pilot study aimed to identify neuroanatomical predictors of cognitive performance in patients with iNPH. Background: Idiopathic normal pressure hydrocephalus (iNPH) is a specific…Unusual Neuronal Intranuclear Inclusion Disease (NIID) with initial presentation mimicking recurrent Transient Global Amnesia (TGA)
Objective: Our aim is to report an unusual Neuronal intranuclear inclusion disease (NIID) case of a woman who initially presented recurrent Transient Global Amnesia (TGA)…Safety profile of pimavanserin therapy in elderly patients with neurodegenerative disease-related neuropsychiatric symptoms: a Phase 3b study
Objective: To evaluate the safety profile of pimavanserin in patients with neuropsychiatric symptoms related to neurodegenerative disease (NDD). Background: Patients with NDD including Parkinson’s disease…Evaluation of a novel Phosphodiesterase 5 inhibitor as a potential therapeutic agent in P301S transgenic mouse model of tauopathy.
Objective: In the current study, we evaluated a newly developed compound with a 1,3,5-trisubstituted pyrazoline scaffold with an improved PDE5 inhibitory potency as a potential…Phenotypic characterization of 104 patients with Progressive Supranuclear Palsy: A Tertiary care experience from South India
Objective: To prospectively evaluate and subtype the patients of Progressive supranuclear palsy being referred to a tertiary care movement disorders facility in South India. Background:…CSF tau reflects long-term outcome of patients with idiopathic normal pressure hydrocephalus: a longitudinal retrospective study.
Objective: To predict long-term clinical outcome of iNPH patients through a panel of neurodegeneration-related CSF biomarkers. Background: Idiopathic normal pressure hydrocephalus (iNPH) is a neurodegenerative…Incremental Hospitalizations and Associated Costs of Co-existing Dementia in Patients with Parkinson’s Disease Psychosis: An analysis of US Medicare Beneficiaries
Objective: To evaluate incremental hospitalizations and costs among Medicare patients with Parkinson's disease psychosis (PDP) vs. PDP+dementia (PDP+D). Background: Research examining hospitalizations and costs of…In vivo positive amyloid PET in a patient with PDD, always reliable?
Objective: To describe a singular case of an early-onset Parkinson disease (PD) patient with PD dementia who presented in vivo positive 18 F-Flutebetamol PET but…A vicious cycle of karyopherin abnormalities in synucleinopathies
Objective: This study aims to investigate the role of karyopherin abnormalities in the onset and progression of synucleinopathies. Background: Despite differences in clinical manifestations, Parkinson’s…Rapidly progressive dementia – catatonia – myoclonus in 80 years old patient: An unusual case
Objective: Objective:Sporadic Creutzfeldt-Jakob Disease (sCJD) will be challenging to differentiate from other diseases, like NMDA autoimmune encephalitis (AE). The classic rapidly progressive dementia phenotype that…
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