Long-term follow-up of subthalamic nucleus deep brain stimulation for Parkinson’s disease: survival and disability milestones
Objective: To characterize retrospectively the long-term survival of 109 PD patients after 8 years of STN-DBS and to identify the incidence of the milestones of…Robust methods for missing covariates in longitudinal studies with application to biomarker research in Parkinson’s disease dementia
Objective: We propose a nonparametric method for handling different types of missing covariates in longitudinal studies. We show that the proposed method outperforms multiple standard…FACIAL EMOTION EXPRESSIVITY IN PARKINSON’S AND ALZHEIMER’S DISEASES
Objective: We here aimed to comprehensively investigate facial emotion expressivity in Parkinson’s disease (PD) and Alzheimer’s disease (AD) patients compared to healthy controls (HCs). Background:…Sex-specific factor analysis-derived profile of neuropsychiatric symptoms predicting dementia conversion in Parkinson’s disease
Objective: Neuropsychiatric symptoms (NPS) are closely associated with cognitive decline in patients with Parkinson’s disease (PD). We investigated which baseline profile of NPS predicts the…Patterns of early-phase 18F-FP-CIT PET images and the risk of dementia conversion in Parkinson’s disease
Objective: This study aims to investigate the prognostic relevance of the patterns of early-phase 18F-fluorinated N-3-fluoropropyl-2-beta-carboxymethoxy-3-beta-(4-iodophenyl) nortropane (18F-FP-CIT) positron emission tomography (PET) images in patients…Critical appraisal of economic evaluation of biomarkers used for screening dementia
Objective: The objective of this study was to assess the cost effectiveness of biomarkers used for early diagnosis of dementia disorders. Background: Dementia remains a…Testamentary Capacity Assessment Tool (TCAT): An update report
Objective: The present study reviews all studies about TCAT and its use in clinical settings, as well as its validation in different cultures. Background: TCAT…Plasma Alzheimer’s disease biomarkers and cognitive progression in Parkinson’s disease
Objective: To evaluate the relationship between plasma Alzheimer's disease biomarkers and cognitive progression in Parkinson's disease Background: Plasma phosphorylated tau (ptau) isoforms have been recently…Predicting the development of dementia in patients with Parkinson’s disease by comparing neurosteroids in the blood level
Objective: To increase the reliability of the development of dementia in patients with PD by a comparative assessment of clinical scales and neurosteroids Background: Parkinson's…Investigating genetic risk factors for Lewy body dementia
Objective: We aim to investigate the genetic mutations related to the development of dementia in Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB)…
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