Evaluation of Neuroprotective Effect of Terminalia macroptera on Rotenone Induced Parkinson’s Disease in Mice
Objective: This study investigates the neuroprotective effects of an aqueous extract of Terminalia macroptera (AETM) in a rotenone-induced Parkinsonism mouse model. Background: Parkinson’s disease (PD)…The neuroprotective effects of Echinacoside on α-synuclein fibril-induced Parkinson’s disease mice model
Objective: This study further investigates the ameliorative effects of ECH on neurobehavioral abnormalities and nigrostriatal dopaminergic system impairment in α-synuclein preformed fibrils (α-Syn PFFs)-induced PD…Chronic DBS Stimulation’s effects after 1-hour off stimulation
Objective: This study investigates the changes in local field potential (LFP) activity during chronic deep brain stimulation (DBS) in patients with Parkinson's disease (PD) during…Cognitive and Neuropsychiatric Dysfunction is Associated with Corticostriatal Synucleinopathy in the Alpha-Synuclein Preformed Fibril Rat Model of Parkinson’s Disease
Objective: To investigate the role of corticostriatal synucleinopathy on behavioral function in an alpha-synuclein preformed fibril (a-Syn PFF) rat model of Parkinson’s disease (PD). Background:…The efficacy and safety of continuous subcutaneous infusion therapy with foslevodopa/foscarbidopa
Objective: To clarify the actual status of CSCI therapy, cases in which CSCI therapy was started at our hospital were investigated. Background: Continuous subcutaneous infusion…A Biomarker-Directed Approach to the Early Diagnosis of Parkinson’s Disease Using Artificial Intelligence and Machine Learning
Objective: The main purpose of this study was to assess how AI and ML methods integrate multiple biomarkers for diagnosing Parkinson’s Disease (PD) to improve…Metabolomic Profiling in an Egyptian Cohort Reveals Altered Phenylalanine Metabolism and Suggests a Role for Trans-Cinnamate in Parkinson Disease
Objective: Investigate the associated metabolic changes in PD via a comprehensive metabolic analysis with a focus on phenylalanine (dopamine precursor) metabolism and its impact on…Profiling Neural Protein Dopaminylation in Parkinson’s disease
Objective: The hallmark of Parkinson’s Disease is motor dysfunction from the decline in dopaminergic cells in the substantia nigra (SN), leading to the development of…Mathematical and Computational Modeling Prototype to Understand the Evolution of Parkinson’s disease using Four Differential Equations
Objective: Apply four differential equations to generate projections considering the effect of dopamine on Parkinson’s disease progression, leading to the development of an initial prototype…Detection and classification of Parkinson’s disease from neuroimaging modalities using machine learning and artificial intelligence: a systematic review
Objective: This systematic review evaluates performance of machine learning (ML) and artificial intelligence (AI) techniques applied to neuroimaging modalities in differentiating Parkinson’s disease (PD) patients…
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