Combination Antiretroviral therapy (cART)-induced cerebellar and prefrontal cortex disorders: A Study on the impact of Naringenin and Quercetin
Objective: This study was designed to investigate the therapeutic potential of selected bioflavonoids on cART-induced neurological disorders. Background: Long term usage of combination antiretroviral therapy…Identification of genetic alterations and SNCA mutation in Parkinson’s disease patients of Coimbatore Population, India
Objective: The aim of the study is to analyze the genetic alterations in SNCA gene and dopamine transporter in 22 PD patients of Coimbatore population.…The dopamine receptor antagonist haloperidol enhances beta and gamma oscillations and bursts in the motor cortex
Objective: We aimed to investigate the changes in oscillatory activity in the motor cortex (MCtx) and the sensorimotor cortex (SMCtx) of rats after acute injection…Restless Leg Syndrome In Men: Examination Of Early Non-Motor Clinical Signs Of Parkinson’s Disease
Objective: Restless Legs Syndrome (RLS) is a disorder characterized by an abnormal sensation, some sort of dysesthesia, which cannot be described especially on the limbs.…Brain neurotransmitters and neuropeptides alternations in Parkinson’s induced mouse models
Objective: Present study aimed to investigate the changes in brain neurotransmitters and neuropetides in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse models of PD. Background: Parkinson’s disease (PD), a…Decreased serum alpha-synuclein in patients with Restless Legs Syndrome and association with SNCA-Rep1 polymorphism
Objective: To investigate whether α -synuclein levels are altered in serum and saliva in patients with RLS and explore influence of the SNCA-Rep1 microsatellite repeat…Quercetin administration abrogates the Parkinson’s disease (PD)-like motor and non-motor symptoms and attenuates the behavioral, neurochemical and biochemical deficits induced by rotenone toxicity in rats
Objective: The present study was carried out to investigate the preventive and therapeutic effects of quercetin (a flavonol) against rotenone-induced neurotoxicity. Background: Rotenone (pesticide) induced…Movement Disorders in Post Stroke Patients: A Retrospective Analysis
Objective: To review the prevalence of various movement disorders in post stroke patients at a tertiary, academic center and to characterize the therapeutic response to…How Parkinson’s Disease Affects Value-Based Decisions
Objective: Parkinson’s Disease (PD) is a degenerative motor disease that causes subtle deficits in decision-making as a result of striatal dysfunction due to dopamine depletion.…Enhancing the Proteasomal Degradation of Alpha Synuclein: “The Hallmark” to attenuating the Progression of Parkinson’s Disease
Objective: The research aimed at preventing the accumulation of Alpha Synuclein in order to prevent it's accumulation. It is imperative that we also establish that…
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