Reduced vesicular storage of catacholamines enhance MPTP-induced death of dopaminergic neurons in locus coeruleus and olfactory bulb
Objective: In this study, we employed heterozygous knockout (vmat2+/-) mice to investigate the influence of reduced vesicular storage of catacholamines on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-impaired dopaminergic neurons…Neuroprotective role of Tinospora cordifolia in MPTP induced Parkinsonian mouse model
Objective: To evaluate the neuroprotective effect of Tinospora cordifolia aqueous extract (TCAE) in Parkinsonian mice. Background: Parkinson’s disease, an age related neurodegenerative disorder, is characterized…EEG microstates changes in response to increase in dopaminergic stimulation in treated typical Parkinson’s disease patients without clinical fluctuations
Objective: Neurotropic drugs may modulate Electroencephalography (EEG) microstates (MS), but there are no works showing EEG MS default-mode network changes in response to dopaminergic stimulation…Catecholamines interrelation in plasma of early diagnosed treatment-naive patients with Parkinson disease
Objective: To investigate the interrelation of catecholamines in the blood plasma of healthy people and PD patients. Background: The study “START-1” was funded by Investment…Relationship between Age-related Frailty and Intra-individual Variability of Reaction Time in Healthy Seniors: Implications for Parkinson’s disease
Objective: To investigate the relationship between age-related frailty and intra-individual variability of reaction time in normal ageing people. Background: The neurobiological processes of normal aging…The use of DaT-SPECT scanning in the differential diagnosis of Parkinsonism: Are guidelines being followed?
Objective: The aim of this study was to assess the adherence of a UK National Health Service (NHS) Parkinson’s disease service to National Institute for…Classification of Dopaminergic-State and Motor Activity by Theta, Beta and Gamma Activity in Parkinson’s Disease
Objective: To test whether machine learning algorithms are suitable to classify dopamine and behavioral states in Parkinson’s patients (PD). Background: While motor symptoms of PD…Training in parkinsonism among health providers in Cameroon
Objective: To describe the knowledge of parkinsonian movement disorders in a sample of Cameroonian health providers and the impact of a basic training course. Background:…Contribution of individual motor signs to striatal dopamine deficiency in parkinsonism
Objective: The primary aim of the study was to investigate if any individual motor sign could be used clinically to predict striatal dopamine deficiency. Secondary…Striatal dopamine function in multiple system atrophy and progressive supranuclear palsy: A meta-analysis of imaging studies
Objective: To investigate differences in striatal presynaptic dopamine function between multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) using combined data from all available…
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