The effect of dopamine on global versus specific inhibitory control in Parkinson’s disease
Objective: To evaluate the effect of dopaminergic medication on inhibitory control using a novel go/no-go task in Parkinson's disease (PD). Global cognition and motor examination…Reduced lifespan and climbing ability observed in the overexpressing human α-synuclein without heat shock protein CNB115 in Parkinson’s disease drosophila line
Objective: To investigate the neurotoxic role of overexpressing α-synuclein without Heat Shock Protein CNB115 (HSP115) in Parkinson's disease Drosophila line. Background: Parkinson's disease (PD) is…Prevalence of impulse control disorders among adult Filipino patients with idiopathic Parkinson’s disease seen at a tertiary center in Manila
Objective: (1) To determine the prevalence and severity of Impulse Control Disorders (ICDs) in adult Filipino patients with idiopathic Parkinson's disease seen at a tertiary…Consolidation of learning and memory in Parkinson’s disease
Objective: To determine if Parkinson's disease causes an impairment in the ability to consolidate learning into long-term memory and to determine if this deficit is…Subthalamic nucleus deep brain stimulation modulate catecholamine levels with significant relations to clinical outcome after surgery in patients with Parkinson’s disease
Objective: Because subthalamic nucleus deep brain stimulation is effective in L-3,4-dihydroxyphenylalanine responsive patients with Parkinson's disease (PD), the preoperative catecholamine levels may affect the effect…Functional characterisation and the selective vulnerability of SNCA (A30P) patient-derived midbrain dopaminergic neurons to ER stress
Objective: To functional characterise and phenotype the genetic Parkinson's disease (PD) patient with an A30P point mutation in SNCA using midbrain dopaminergic neurons (mDANs) vs…Dopamine reduces Parkinson’s tremor through increased thalamic inhibition
Objective: To identify cerebral mechanisms explaining the effects of dopamine on rest tremor in Parkinson's disease. Background: Resting tremor in Parkinson's disease is related to…Anxiety and cognition are associated with dopaminergic dysfunction in de novo Parkinson’s disease
Objective: To explore the relationships between nigrostriatal dysfunction and both neuropsychiatric (including anxiety, depression and apathy) and cognitive symptoms in newly diagnosed, drug-naive Parkinson's disease…Gene expression analysis using the Parkinson’s disease map reveals early effects of alpha-synuclein on PD pathogenesis
Objective: The identification of early disease markers for Parkinson's disease (PD) is essential, since the disease is already in an advanced state when motor symptoms…Exploring structural covariance networks of gray matter in Parkinson’s disease
Objective: To investigate whether structural covariance networks (SCNs) can be used to detect disease-specific patterns of gray matter atrophy in Parkinson's disease (PD) and secondly,…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.