Ferroptosis, a recently identified cell death, as a therapeutic target for Parkinson’s disease.
Objective: We aim to determine in a cell model neuroprotective effects of targeting lipoxygenases (LOXs), central players in Ferroptosis, a novel regulated iron-dependent cell death…Extracellular α-synuclein enters dopaminergic neurons by modulating flotillin-1-assisted DAT endocytosis
Objective: In this study, we examine the regulatory role of flotillin-1 in dopamine transporter (DAT) trafficking and the impact of extracellular α-synuclein (αS) on this…Chlorogenic acid attenuates the MPTP induced apoptosis in Parkinson’s disease mouse model through pAkt signaling pathway
Objective: This study deals to investigate and explore the anti-apoptotic and molecular mechanisms of CGA in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced Parkinsonian mice model. Background: The debilitating…Relative Preservation of Serotonergic Function Increases Response to Treatment in Early PD
Objective: To investigate interactions between the serotonergic and dopaminergic systems in early PD as related to (i) response to treatment and (ii) dopamine (DA) release,…Yerba Mate (Ilex paraguaiensis) protects dopaminergic neurons degeneration and improve their maturation in culture
Objective: To evaluate the effect of Mate leaves extracts on the survival and maturation of dopaminergic neurons in vitro. Background: Parkinson's disease (PD) is caused…Primary familial brain calcification – The impact of calcifications on the development of motor symptoms
Objective: The aim of the present study was to investigate whether the nigro-striatal system in a genetic mouse model of primary familial brain calcification (PFBC)…Controlled neural organoids grafting promotes functional recovery in experimental parkinsonism
Objective: We propose that the striatal transplantation of 3D-neural organoids of controlled cell size and cell content, named "Controlled Neural Organoids" (CNOs), could circumvent the…Vitamin B3 and Neurodevelopment in Parkinson’s Disease
Objective: This study aimed to investigate the potential of vitamin B3 to promote the conversion of stem cells to mature central nervous system (CNS) neurons.…Dopaminergic stem cells reside in the rostral migratory stream
Objective: To analyze if the adult rostral migratory stream (RMS) harbors neural stem cells with the potential to create dopaminergic neurons for the olfactory bulb…A53T mutant human α-synuclein BAC transgenic mice as a model for Parkinson’s disease
Objective: The aim of this study is to create mouse models reproducing the course of PD pathology and symptoms. Background: Parkinson's disease (PD) is a…
- « Previous Page
- 1
- …
- 7
- 8
- 9
- 10
- 11
- …
- 15
- Next Page »