Multivariate analysis of writer`s cramp: a study with advanced multi-channel microelectrode recording system
Objective: To quantify difference in WC patients with Concordant mirror movements(MMs) from those with Discordant MMs. Background: Invasive methods are encouragive for quantitative analysis. The…Abnormal patterns of action selection in the dominant motor cortex in writer’s cramp
Objective: To test if (1) abnormal right dorsal premotor cortex (dPMC) to left primary motor cortex (M1) interaction during writing with right hand contributes to…A Pilot Multiparametric MEG Study of coherence in generalized and cervical dystonia
Objective: To explore functional connectivity at network level with MEG, pre and post-administration of medications, in generalized and cervical dystonia. Background: The underlying mechanisms of…Motor stress elicits dystonia-like movements in a pharmacological mouse model for Rapid-Onset Dystonia-Parkinsonism (DYT12)
Objective: To study if a mild stressful trigger by motor activity leads to development of dystonia-like movements in a pharmacological mouse model for DYT12. Background:…Exploring the neurophysiology of cervical dystonia using TMS-EEG
Objective: To probe cortical excitability and inhibition in primary motor cortex and supplementary motor area (SMA) in cervical dystonia Background: Cervical Dystonia (CD) is characterized…Brainstem connection of Writer’s cramp: Electrophysiological correlates
Objective: In this study, we explored the involvement of brainstem in Writer’s cramp (WC) patients through pre-pulse inhibition of blink reflex and Start-React paradigm. Background:…Dystonia-like phenotype in a DYT1 rat model after peripheral trauma
Objective: Establishment and characterization of a DYT1 rat model with dystonia-like movements after sciatic nerve crush injury. Background: Penetrance of DYT1 dystonia is markedly reduced…A kinematic analysis of finger tapping in dystonia
Objective: To perform a computerised analysis of finger tapping in patients with dystonia and healthy controls in order to develop a better understanding of the…Head turning onset and velocity in response to a peripheral visual stimulus in cervical dystonia patients, their unaffected relatives with and without abnormal temporal discrimination and healthy controls.
Objective: We postulate that cephalomotor responses (onset of head turning and speed of head turning) to the appearance of a novel peripheral visual stimulus will…Brain volume changes in relation to intracortical inhibition and clinical benefit of pallidal stimulation in dystonia: a combined VBM and TMS study.
Objective: To explore the relationship between brain morphology, clinical effects of bilateral pallidal stimulation (GPi DBS) and intracortical inhibition of the motor cortex in patients…
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