Synergistic effects of short pulse and directional deep brain stimulation of the thalamic ventral intermediate area for essential tremor
Objective: The aim of this study was to investigate differential and synergistic effects of short pulse and directional deep brain stimulation in the ventral intermediate…Bilateral focused ultrasound thalamotomy for essential tremor (BEST-FUS trial): safety and efficacy proof of principle
Objective: The goal of this study was to assess the feasibility, safety and efficacy of staged, bilateral, focused ultrasound thalamotomies for essential tremor. Background: Essential…Comparative connectivity correlates of dystonic and essential tremor deep brain stimulation
Objective: To analyze the pathophysiology of dystonic tremor (DT) and essential tremor (ET) and to reveal the optimal deep brain stimulation (DBS) target for these…Deep Brain Stimulation Surgery and Clinical Characteristics of Essential Tremor in a Cohort of Veterans
Objective: To review clinical characteristics of essential tremor (ET) in patients who underwent deep brain stimulation (DBS) surgery. Background: DBS surgery is an effective treatment…Delayed lesion adverse effects of gamma knife radiosurgical thalamotomy for essential tremor
Objective: To describe a novel case of gamma knife radiosurgical (GKRS) thalamotomy for treatment of refractory essential tremor (ET) with delayed onset adverse effects due…Satisfaction and impact on quality of life in patients with essential tremor treated with High Intensity Focused Ultrasound (HIFU) thalamotomy
Objective: To analyze the improvement in quality of life (QOL) and treatment´s satisfaction patients with essential tremor (ET) treated with HIFU thalamotomy. Background: Tremor is…The Role of Directional Configuration for Essential Tremor: A Single Center Experience
Objective: To describe the programming criteria and patient characteristics for use of directional versus omnidirectional configurations for deep brain stimulation (DBS) in patients with Essential…An Open-Label, Phase 1b Study of the Neuroactive Steroid GABAA Receptor Positive Allosteric Modulator SAGE-324 in Essential Tremor
Objective: This single dose, open-label, Phase 1b study assessed the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of SAGE-324 in otherwise healthy patients with Essential…Cortical network fingerprint and prediction of deep brain stimulation-induced speech impairment in essential tremor
Objective: To gain insights into brain areas associated with stimulation-induced dysarthria (SID) and to predict stimulation-induced worsening of intelligibility in essential tremor (ET) patient with…Efficacy and safety of CX-8998 in T-CALM, a randomized, double-blind, placebo-controlled, phase 2a trial in participants with essential tremor: subgroup analysis by baseline tremor severity
Objective: Evaluate efficacy and safety of CX-8998 in essential tremor (ET) as a function of baseline tremor severity. Background: CX-8998, a selective modulator of T-type…
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