Comparing the Connectivity of Thalamic Deep Brain Stimulation Sites in ET and ET Plus Syndrome
Objective: To examine differences in structural connectivity of deep brain stimulation (DBS) sites in patients with essential tremor (ET) and essential tremor plus syndrome (ET-plus).…Diagnostic accuracy of susceptibility map-weighted MRI for discriminating tremor-dominant Parkinson’s disease and essential tremor
Objective: We investigated the diagnostic accuracy of nigrosome using susceptibility map-weighted imaging (SMwI) in distinguishing tremor-dominant Parkinson's disease (PD) and essential tremor (ET). Background: Tremor is…KINETIC 2: An ongoing phase 2b, randomized, dose-response study of SAGE-324/BIIB124 for the treatment of essential tremor
Objective: KINETIC 2 (NCT05173012) is an ongoing, phase 2b, randomized, double-blind, placebo-controlled, dose-response study that aims to evaluate the efficacy, safety, and tolerability of SAGE-324/BIIB124…Success of MRI-guided focused ultrasound thalamotomy after failure of Gamma Knife radiosurgery for essential tremor
Objective: To study the effect of MR-guided focused ultrasound (MRgFUS) targeting the ventral intermediate nucleus of the thalamus (VIM) after a failed ipsilateral Gamma Knife…Structural MRI and tremor analysis in the differential diagnosis of rest tremor
Objective: This study aimed to differentiate between essential tremor with rest tremor (rET) and tremor-dominant Parkinson’s disease (td-PD) patients through a machine learning (ML) approach…Serum neurofilament light-chain concentrations in essential tremor: A case-control study
Objective: We sought to investigate the concentrations of serum neurofilament light-chain (NfL) in essential tremor (ET) patients and healthy controls. Background: Essential tremor is a…Tremor Reduction Using DBS: Outcomes of a Real-world, Prospective, Multicenter Essential Tremor Registry
Objective: In this report, preliminary data will be presented from a prospective, multicenter, international Essential Tremor (ET) outcomes study in which patients received a multiple…Active contact proximity to the CTT predicts initial therapeutic current requirement in DBS for ET: an application of 7T MRI
Objective: We sought to characterize the impact of deep brain stimulation (DBS) active contact location relative to the cerebellothalamic tract (CTT) on stimulation parameters in…The spatial and spectral organization of thalamo-cortical connectivity in patients with essential tremor
Objective: To identify cortical areas coupled to the ventral intermediate nucleus of the thalamus (VIM) in patients with essential tremor (ET). Background: ET is a…Late onset cerebellar ataxia in patients treated with VIM DBS
Objective: To highlight the predictors for onset of cerebellar ataxia in patients treated with deep brain stimulation (DBS) of the Thalamic Ventral Intermediate Nucleus (VIM)…
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