MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Experimental therapeutics"

  • 2017 International Congress

    AAV-mediated over-expression of VEGF-B in PINK1 gene knockout rats increases striatal dopamine content

    T. Falk, M. Bartlett, D. Muller, B. Silashki, D. Farrell, K. Parent, M. Heien, S. Sherman (Tucson, AZ, USA)

    Objective: To evaluate overexpression of the neuroprotective vascular endothelial growth factor B (VEGF-B) in a genetic Parkinson’s disease (PD) model. Background: We have shown in…
  • 2017 International Congress

    Identification of a trehalose treatment regimen with potential to be translated into a therapeutic for the treatment of Parkinson’s disease

    J. Koprich, P. Howson, T. Johnston, M. Hill, P. Ravenscroft, J. Brotchie (Toronto, ON, Canada)

    Objective: To evaluate the preclinical efficacy of trehalose and to identify a dosing regimen that can be used to clinically evaluate trehalose as a disease-modifying therapy…
  • 2016 International Congress

    The French experience of liver transplantation for severe neurological forms of Wilson disease

    A. Poujois, R. Sobesky, W. Meissner, E. de Medeiros, C. Vanlemmens, A.S. Brunet, E. Broussolle, J.C. Duclos-Vallée, F. Woimant (Paris, France)

    Objective: To evaluate the efficacy of liver transplantation (LT) in patients with severe neurological forms of Wilson disease (WD) who got clinically worse despite a…
  • 2016 International Congress

    Clinical and neuroimaging outcomes up to 18 years after fetal tissue transplant for Parkinson’s disease

    C. Henchcliffe, J. Carter, A. Hanineva, Y. Kang, J. Babich, S.M. Gollomp, A.P. Strafella, A. Fasano, L.D. Ravdin, N. Hellmers, C. McRae (New York, NY, USA)

    Objective: To characterize clinical and radiological outcomes in 4 patients with Parkinson's disease (PD) at 16-18 years post-transplant of fetal ventral mesencephalic (fVM) tissue into…
  • 2016 International Congress

    Virtual-reality balance training with Nintendo-Wii games improves dynamic balance in Parkinson’s disease patients

    G.H. Lee (Cheon-An, Korea)

    Objective: This study was to investigate the effectiveness of a 8-week virtual reality exercise program designed around the Nintendo Wii (Wii), in improving balance among…
  • 2016 International Congress

    The differentiated treatment of Parkinson’s disease in patients with concomitant diabetes mellitus(DM) type 2

    F.S. Akhmedova, M.K.U. Tukhtamishev (Tashkent, Uzbekistan)

    Objective: To study the state of lipid metabolism in PD patients with concomitant type 2 diabetes with different glucose tolerance and the influence of the…
  • 2016 International Congress

    Influence of treadmill gait training with additional load on motor function, postural instability and history of falls for individuals with Parkinson’s disease: A randomized clinical trial

    L.C.L. Trigueiro, A.V.C. Sousa, G.L. Gama, T.S. Ribeiro, L.G.L.M. Ferreira, C.R. Simão, É.R.V.P. Galvão, E.M.G.S. Silva, C.G. Júnior, A.R.R. Lindquist (Natal, Brazil)

    Objective: The objective of this study was to evaluate the effects of additional load (5% and 10%) with treadmill gait training on the overall motor…
  • 2016 International Congress

    Does physical exercise influence the cognitive domains that predict dementia in Parkinson’s disease?

    C.R.A. Silveira, E.A. Roy, B.N. Intzandt, Q.J. Almeida (Waterloo, ON, Canada)

    Objective: This study aimed to investigate the effects of aerobic and goal-based exercise on memory, language, and visuospatial functions in cognitively normal and impaired individuals…
  • 2016 International Congress

    Classification and recommendation of nonpharmacological therapies for Parkinson’s disease

    T.T.C. Capato, C.H. Fen, E.R. Barbosa (São Paulo, Brazil)

    Objective: A multidisciplinary specialized treatment including physiotherapy, speech and language therapy, occupational therapy (OT) associated to the ideal pharmacological treatment and surgical is recommended to…
  • 2016 International Congress

    Transcranial versus root repeated magnetic stimulation as a treatment of psychogenic movement disorders

    B. Garcin, C. Hubsch, L. Lliescu, L. Naccache, M. Vidailhet, E. Fournier, F. Mesrati, E. Roze, B. Degos (Paris, France)

    Objective: To determine whether the beneficial effect of repeated transcranial magnetic stimulation (rTMS) in psychogenic movement disorders (PMDs) is the consequence of a cortical functioning…
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