Wearable-Derived Gait Biomarkers Predict Disease Severity and Quality of Life in Parkinson’s Disease: A Machine Learning and Mediation Analysis
Objective: To investigate whether wearable-derived gait biomarkers predict disease severity and health-related quality of life in Parkinson’s disease (PD) and to examine the mediating role…Inter-Rater Variability in Motor Assessment Scoring: Measurement Implications for Understanding Movement Disorders in Aging
Objective: To quantify inter-rater agreement in independent clinician scoring of video-recorded MDS-UPDRS Part III assessments, and to characterize the distribution of scoring variability at both…Age-Modulated Gait Adaptations to Progressive Fatigue in Parkinson’s Disease
Objective: To investigate the effect of progressively increasing perceived fatigue on gait biomechanics in people with Parkinson’s disease (PD), considering the potential moderating role of…Biomechanical Analysis of Gait Movement Disorders in Spinal Cord Injury and Its Implications for Rehabilitation Strategies
Objective: To systematically analyze the spatiotemporal, kinematic, and electromyographic gait movement disorders in patients with partial SCI for targeted rehabilitation strategies. Background: Spinal cord injury…Correlating Start Hesitation and Subthalamic Nucleus Activity in Parkinson’s Disease Using Intraoperative Microelectrode Recordings and a Virtual Reality Task
Objective: To investigate the modulations in subthalamic nucleus (STN) signals that are associated with prolonged gait initiation duration in a virtual reality gait task in…Quantitative Assessment of Turning Kinematics and its Association with Parkinson’s Disease Severity
Objective: This study aims to investigate the association between turning performance and disease severity, measured by the MDS-UPDRS and PDQ-39, in people with Parkinson’s disease…Boosting cerebellum/M1 and PPC/M1 communication via tACS to improve cued gait in Parkinson’s disease patients unresponsive to auditory cueing strategies.
Objective: This study aims to test the contribution of Posterior Parietal Cortex – primary motor cortex and cerebellum - M1 pathways in decreasing gait variability…Sleep Disturbance and Sleep Fragmentation as Correlates of Gait Deterioration and Fall-Related Outcomes in Parkinson’s Disease: A Systematic Review
Objective: To review whether sleep disturbance, particularly sleep fragmentation and reduced sleep efficiency, is associated with gait deterioration, freezing of gait, and fall-related outcomes in…Gait parameters, Imaging features, and CSF tap test in idiopathic Normal Pressure Hydrocephalus (iNPH) Is composite testing the way to go
Objective: To analyze the positive predictive values of specific imaging findings for CSF-TT responsiveness and shunt responsivenessTo determine whether composite diagnostic models incorporating CSF-TT and…Clinical Gait Traits and Cerebellar-PPN Functional Connectivity Abnormalities in Early and Moderate-to-Advanced PD with Gait Disturbance via Perceptual Technology and MRI
Objective: To investigate clinical gait characteristics and cerebellar-pedunculopontine nucleus (PPN) functional connectivity (FC) changes in early-stage and moderate-to-advanced-stage Parkinson’s disease (PD) with gait disturbance using wearable…
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