FREEZESTEP = DALFLEX
Objective: Freezing of gait(FOG) is defined as a brief, episodic absence or marked reduction of forward progression of the feet despite the intention to walk.…Decreased mesencephalic locomotor region activation explains loss of presynaptic inhibition during step initiation in people with Parkinson´s disease with freezing of gait
Objective: To investigate if decreased mesencephalic locomotor activation (MRL) activation during step initiation in an-event related fMRI protocol would explain the loss of presynaptic inhibition…Factors contributing to prefrontal cortical activity during walking and its response to dual-tasking in Parkinson’s disease
Objective: We examined the contribution of clinical, cognitive, and gait characteristics to prefrontal cortex (PFC) activity during walking and its response to dual-task in people…Brain activity of the emotional circuit in Parkinson’s disease patients with freezing of gait
Objective: The aim of this observational study was to assess brain functional MRI (fMRI) activity during a “FoG observation task” in PD-FoG patients relative to…Longitudinal structural and functional brain alterations in Parkinson’s disease patients with freezing of gait
Objective: To investigate the cortical/subcortical grey matter (GM) changes and network functional alterations in PD-FoG patients, in PD developing FoG (PD-FoG-converters) and PD not developing…Tractography Analysis of the Pedunculopontine Nucleus Correlates with Gait Impairment in Parkinson’s Disease
Objective: Our objective was to correlate pedunculopontine nucleus (PPN) connectivity with quantitative gait metrics in Parkinson’s disease (PD) using diffusion tensor imaging (DTI). Background: Gait…Structural and functional cerebellar alterations in Parkinson’s disease with postural instability and gait disorders
Objective: This study aimed at assessing structural and functional cerebellar alterations in Parkinson’s disease patients with postural instability and gait disorders (PD-PIGD). Background: Brain structures…Identifying neural signatures of Parkinson’s disease that predict decline in gait and postural control
Objective: To identify Parkinson’s disease [PD] specific patterns in the brain using a multi-modal neuroimaging design and use these to predict gait decline. Background: Gait…Prefrontal cortical activity and the control of walking in people with freezing of gait
Objective: To investigate the influence of freezing of gait (FoG) on automaticity of walking in people with Parkinson’s disease (PD). Background: A hallmark of healthy…Deficient Balance Mechanisms during Walking in People with Parkinson’s Disease
Objective: Investigate whether people with Parkinson’s disease (PD) have deficient balance mechanisms following visual perturbations during walking. Background: We recently showed that maintaining upright balance…
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