Parameterization of Intraoperative Human Microelectrode Recordings: Linking Action Potential Morphology to Brain Anatomy
Objective: To investigate whether single-unit spike morphology from intraoperative microelectrode recordings (MER) can provide anatomical and physiological insights relevant to deep brain stimulation (DBS) targeting.…Comparison of subthalamic nucleus and globus pallidus internus as deep brain stimulation targets for freezing of gait in Parkinson’s disease
Objective: To compare the short-term effects of deep brain stimulation (DBS) in subthalamic nucleus (STN) and globus pallidus internus (GPi) on freezing of gait (FOG)…Parkinsonism following Chronic Disulfiram Overdose
Objective: To describe the effect of chronic intake of disulfiram Background: Background- Drug induced parkinsonism is one of the commonest causes of non-degenerative parkinsonism. Typical…Exploring the Role of Aperiodic and Periodic Spectral Activity in Guiding Deep Brain Stimulation Electrode Selection for Childhood Dystonia
Objective: To evaluate the potential of aperiodic and periodic neural activity in guiding clinical deep brain stimulation (DBS) programming for children with dystonia. Background: DBS…Long-term results of pallidal deep brain stimulation in patients with Huntington’s disease
Objective: To analyze long-term results of pallidal (GPi) deep brain stimulation (DBS) in patients with Huntington's disease (HD). Background: In HD, DBS is suggested to…GPi Stimulation shows Immediate Effects in Motor Improvement within Pediatric Patients with Movement Disorders
Objective: This study was conducted in order to determine whether GPi stimulation has immediate clinical effect in patients with dystonia who underwent Deep Brain Stimulation…Randomness and bursting of pallidal spiking activity correlates with DBS outcome in Parkinson’s disease and dystonia
Objective: The aim of the current study is to characterize spontaneous pallidal neuronal activity in patients with Pakninson’s disease (PD) and dystonia with different clinical…Tracking Physiological Biomarker Activity in the Globus Pallidus Internus in Two Dystonia Patients Implanted with Medtronic Percept™
Objective: Explore potential biomarkers in dystonia patients implanted with Medtronic Percept™. Background: Though highly variable in presentation and underlying cause, individuals with dystonia present with…Clinical Improvement after Deep Brain Stimulation is associated with the Suppression of Pallidal low-frequency Oscillations in Patients with Dystonia
Objective: to investigate the relationship between pallidal activity and clinical response to deep brain stimulation (DBS) of the globus pallidus internus (GPi) Background: GPi-DBS is…Status Dystonicus is a Distinct State Characterized by Pallidal Beta-band Activity
Objective: To identify distinct pallidal local field potential (LFP) signatures characterizing status dystonicus (SD) from non-SD dystonia. Background: SD is a poorly understood neurological emergency…
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