Longitudinal MRI Study of Hippocampal Subfields Morphometry in Early Parkinson’s Disease
Objective: This prospective cohort study longitudinally investigated hippocampal subfield shape deformation and atrophy in early-stage Parkinson’s Disease (PD), using spherical harmonic-based shape analysis. Background: Hippocampal…LED Light as an Inductor of Optogenetic Activation of Astrocytes in Multiple System Atrophy
Objective: The pathogenesis of Multiple System Atrophy (MSA) involves the spread of misfolded α-synuclein from nerve cells to glia and dysfunction of mitochondria and proteasomes,…Predictor of post-deep brain stimulation cognitive decline in Parkinson’s disease patients
Objective: Deep brain stimulation (DBS) is a highly effective treatment for Parkinson’s disease (PD) motor symptoms; however, its benefits can be overshadowed by side effects…Lewy Pathology correlates with neuroinflammation in the hippocampus of Synucleinopathy patients in a subregion specific manner
Objective: The objective of this study is to examine the sub-regional differences in neuroinflammation (NI) in response to Lewy pathology (LP) within the hippocampus of…Hippocampal-striatal interaction and cognitive decline in Parkinson’s disease with mild cognitive impairment
Objective: We aimed to investigate the interaction between hippocampus and dopaminergic pathways in PD with mild cognitive impairment (PD-MCI). Background: Dysfunction of striatal dopaminergic neurotransmitter…Increased Resting Anterior Hippocampus Metabolism and Hippocampus Subfields Structural Abnormalities in Functional Tremor Patients: FDG- PET Study and Volumetric MRI Study
Objective: In this study, we focused on identifying the resting 18F-FDG PET brain imaging patterns in the limbic region and measuring the MRI volumes of…Neuroprotective Efficacy of Ethanolic Extract from Amorphophallus Paeoniifolius Tuber Against Haloperidol-Induced Parkinson’s Disease Model
Objective: This study aimed to evaluate the neuroprotective and antiparkinsonian effects of the ethanolic extract of Amorphophallus paeoniifolius tuber (APT) against haloperidol-induced Parkinson’s Disease (PD)…Hippocampal volume in Parkinson’s Disease in south India
Objective: To analyse hippocampal volume differences among the patients with Parkinson’s disease and healthy individuals. Background: In humans, hippocampus is involved in regulation of emotions,…Polyaromatic hydrocarbons in Ambient Particulate Matter (PM 2.5) mediate neurodegeneration through the olfactory-brain axis in C57BL/6 mice
Objective: To delineate the molecular mechanisms involved in bidirectional olfactory-brain-induced neurodegeneration caused by exposure to ambient particulate matter (PM2.5). Background: Air pollution has been linked…Association between changes in hippocampal volumes, cognition, and CSF markers in Parkinson’s Disease
Objective: To assess whether changes in hippocampal subfield volumes are associated with cognition or CSF β-amyloid 1–42 (Aβ42) levels in Parkinson’s Disease (PD). Background: Hippocampal…