MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Hippocampus"

  • 2025 International Congress

    Longitudinal MRI Study of Hippocampal Subfields Morphometry in Early Parkinson’s Disease

    T. Wu, S. Ng, T. Teo, X. Choi, D. Heng, S. Neo, Z. Xu, K. Tay, W. Au, E. Tan, L. Chan, L. Tan, T. Welton (Singapore, Singapore)

    Objective: This prospective cohort study longitudinally investigated hippocampal subfield shape deformation and atrophy in early-stage Parkinson’s Disease (PD), using spherical harmonic-based shape analysis. Background: Hippocampal…
  • 2025 International Congress

    LED Light as an Inductor of Optogenetic Activation of Astrocytes in Multiple System Atrophy

    F. Kiryukhin, D. Labunskiy, S. Kiryukhina, O. Zheleznikova (Moscow, Russian Federation)

    Objective: The pathogenesis of  Multiple System Atrophy (MSA) involves the spread of misfolded α-synuclein from nerve cells to glia and dysfunction of mitochondria and proteasomes,…
  • 2025 International Congress

    Predictor of post-deep brain stimulation cognitive decline in Parkinson’s disease patients

    L. Montaser-Kouhsari, E. Narinsky, M. Fox (Boston, USA)

    Objective: Deep brain stimulation (DBS) is a highly effective treatment for Parkinson’s disease (PD) motor symptoms; however, its benefits can be overshadowed by side effects…
  • 2025 International Congress

    Lewy Pathology correlates with neuroinflammation in the hippocampus of Synucleinopathy patients in a subregion specific manner

    E. Luna, K. Cousins, S. Emrani, K. Luk, V. Lee, E. Lee, D. Weintraub, S. Xie, A. Chen-Plotkin, F. Bennett, D. Irwin (Philadelphia, USA)

    Objective: The objective of this study is to examine the sub-regional differences in neuroinflammation (NI) in response to Lewy pathology (LP) within the hippocampus of…
  • 2025 International Congress

    Hippocampal-striatal interaction and cognitive decline in Parkinson’s disease with mild cognitive impairment

    S. Tan, X. Zhang, J. Wen, X. Xu, Z. Zhang, J. Xu (Hangzhou, China)

    Objective: We aimed to investigate the interaction between hippocampus and dopaminergic pathways in PD with mild cognitive impairment (PD-MCI). Background: Dysfunction of striatal dopaminergic neurotransmitter…
  • 2024 International Congress

    Increased Resting Anterior Hippocampus Metabolism and Hippocampus Subfields Structural Abnormalities in Functional Tremor Patients: FDG- PET Study and Volumetric MRI Study

    M. Ahmed, P. Dupont, S. Du Plessis, J. Warwick, A. Doruyter, E. Lee Pan, J. Carr (Cape Town, South Africa)

    Objective: In this study, we focused on identifying the resting 18F-FDG PET brain imaging patterns in the limbic region and measuring the MRI volumes of…
  • 2024 International Congress

    Neuroprotective Efficacy of Ethanolic Extract from Amorphophallus Paeoniifolius Tuber Against Haloperidol-Induced Parkinson’s Disease Model

    R. Kumar, S. Choudhary (Handia,, India)

    Objective: This study aimed to evaluate the neuroprotective and antiparkinsonian effects of the ethanolic extract of Amorphophallus paeoniifolius tuber (APT) against haloperidol-induced Parkinson’s Disease (PD)…
  • 2024 International Congress

    Hippocampal volume in Parkinson’s Disease in south India

    R. Kandadai, T. Syed, A. Arora, T. Sd, S. Kola, S. Yaranagula, V. Prasad, R. Alugolu, S. Turaga, R. Borgohain (Hyderabad, India)

    Objective: To analyse hippocampal volume differences among the patients with Parkinson’s disease and healthy individuals. Background: In humans, hippocampus is involved in regulation of emotions,…
  • 2023 International Congress

    Polyaromatic hydrocarbons in Ambient Particulate Matter (PM 2.5) mediate neurodegeneration through the olfactory-brain axis in C57BL/6 mice

    SR. Panda, VGM. Naidu (Guwahati, India)

    Objective: To delineate the molecular mechanisms involved in bidirectional olfactory-brain-induced neurodegeneration caused by exposure to ambient particulate matter (PM2.5). Background: Air pollution has been linked…
  • 2023 International Congress

    Association between changes in hippocampal volumes, cognition, and CSF markers in Parkinson’s Disease

    S. Becker, O. Granert, C. Schulte, K. Brockmann, B. Roeben, M. Bode, M. Timmers, K. Scheffler, W. Maetzler, D. Berg, I. Liepelt-Scarfone (Calgary, Canada)

    Objective: To assess whether changes in hippocampal subfield volumes are associated with cognition or CSF β-amyloid 1–42 (Aβ42) levels in Parkinson’s Disease (PD). Background: Hippocampal…
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