A Pilot Feasibility Study of Medium Chain Triglyceride Nutritional Ketosis and Parkinson’s Disease
Objective: To determine if nutritional ketosis supplemented by medium chain triglycerides (MCT) over the course of 2-3 weeks is acceptable and feasible in patients with…Exploratory delayed-start analysis of PASADENA evaluating the efficacy of prasinezumab on motor progression and motor complications in early-stage Parkinson’s disease
Objective: To evaluate the effect of prasinezumab on motor progression and motor complications in early-stage Parkinson’s disease (PD) using an exploratory delayed-start analysis of Part…Opicapone Improves Global Non-Motor Symptoms Burden in Parkinson´s Disease: An Open-label Prospective Study
Objective: The aim of this study was to analyze the effectiveness of opicapone on global non-motor symptoms (NMS) burden in Parkinson´s disease (PD). Background: Some…Clinical and device-based predictors of improvement in motor experiences of daily living after a short-term multidisciplinary inpatient treatment: a cohort study
Objective: To determine predictors of improvement in motor experiences of daily living (m-EDL) after a multidisciplinary inpatient ‘PD multimodal complex treatment’ (PD-MCT) and clarify the…Optimizing patient-centric clinical outcome assessments for use in Parkinson’s disease clinical trials: Critical Path for Parkinson’s multistakeholder initiative
Objective: To advance patient-centric endpoints for use in early-stage Parkinson’s disease (PD) clinical trials. Background: Limitations with currently available patient-centric clinical outcome assessments (COAs) has…Estimating the Meaningful Within-Patient Change Threshold for the MDS-UPDRS Part III
Objective: To estimate the meaningful within-patient worsening threshold (MWPWT) of the Movement Disorders Society–Unified Parkinson’s Disease Rating Scale (MDS-UPDRS Part III in early-stage Parkinson's disease…A systematic review on physical health education interventions for people with Parkinson’s: content, impact and implementation considerations across Parkinson’s trajectory
Objective: To examine the content of education interventions that promote physical activity (PA) behavior in PwP, and to assess their effectiveness on physical and psychosocial…A Patient-Centered Outcomes Survey in Parkinson’s Disease: Results of Cognitive Pre-Testing
Objective: To validate the Rush Parkinson's Disease Patient-Centered Outcomes Questionnaire (RUSH-PCO-Q). Background: The RUSH-PCO-Q aims to address the lack of patient-centered outcomes in the field…The effect of exercise on pain in Parkinson’s disease: a systematic review
Objective: To perform a systematic review assessing the effects of exercise on pain in people with Parkinson’s disease (PD) (PROSPERO registration CRD42019129154). Background: Chronic pain…iFall: Co-producing an instrumented application prototype for falls reporting in Parkinson’s disease
Objective: To work with those affected by Parkinson’s disease (PD) to co-produce a prototype of an instrumented application for reporting falls (iFall). Background: Falls commonly…
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