MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Levodopa(L-dopa)"

  • 2022 International Congress

    Rapid onset of good ON time and improvement in motor-state stability in aPD patients after treatment with continuous subcutaneous foslevodopa/foscarbidopa

    R. Pahwa, M. Soileau, D. Standaert, V. Fung, T. Kimber, I. Malaty, A. Merola, A. Epstein, C. Yan, A. Alobaidi, A. Shewale, N. Fisseha, A. Jeong, M. Facheris, P. Kukreja, J. Zamudio, J. Aldred (Kansas City, USA)

    Objective: To evaluate time to ON without troublesome dyskinesia (‘good ON’) and patterns of motor-state stability throughout the day in patients with advanced Parkinson’s disease…
  • 2022 International Congress

    Assessment of microstructural changes associated with levodopa-induced dyskinesia in hemiparkinsonian rodents

    M. Bergamino, A. Fuentes, D. Marmion, I. Sandoval, C. Bishop, F. Manfredsson, A. Stokes (Phoenix, USA)

    Objective: To assess white matter (WM) microstructural integrity changes in pre-clinical models of Parkinson’s disease (PD) with levodopa-induced dyskinesia (LID). Background: PD is a neurodegenerative…
  • 2022 International Congress

    Nutritional Status in Advanced Parkinson’s Disease: Preliminary Results.

    N. Ayo (Barakaldo, Spain)

    Objective: To analyze the relationship between nutritional intake and weight aspects in 3 groups of patients with Parkinson's disease (PD) who are receiving different pharmacological…
  • 2022 International Congress

    Use of a wearable medical device for LCIG tube adjustment: a user case

    JHR. Herreros Rodríguez, AEL. Esquivel López, JP. Romero Muñoz, M. Llaguno Velasco (Madrid, Spain)

    Objective: To identify objectively the change in motor symptoms in a patient with Parkinson’s Disease (PD) on levodopa-carbidopa intestinal gel (LCIG) treatment with and without…
  • 2022 International Congress

    Dopamine agonist utilization prior to the initiation of device aided therapy: data from 150 patients with advanced Parkinson’s disease treated with Levodopa Carbidopa Intestinal Gel

    J. Szasz, V. Constantin, K. Orban-Kis, L. Bancu, S. Bataga, R. Neagoe, J. Szederjesi, B. Grigorescu, M. Ciorba, I. Mihaly, K. Kelemen, S. Szatmari (Targu Mures, Romania)

    Objective: Objective: To evaluate the usage of dopamine agonists (DA) as part of the last conventional dopaminergic treatment in a large cohort of consecutive patients…
  • 2022 International Congress

    Impact of foslevodopa/foscarbidopa on key clinical and patient-reported outcomes in patients with aPD: Responder analysis of two Phase 3 clinical trials

    M. Soileau, J. Aldred, A. Antonini, C. Carroll, V. Fung, T. Henriksen, R. Pahwa, D. Santos Garcia, A. Epstein, C. Yan, A. Alobaidi, A. Shewale, A. Spiegel, M. Facheris, J. Zamudio, P. Kukreja, KR. Chaudhuri (Georgetown, USA)

    Objective: To evaluate the effect of foslevodopa/foscarbidopa (LDP/CDP, ABBV-951) on clinical and patient-reported outcomes in advanced Parkinson’s disease (aPD) patients using minimal clinically important difference…
  • 2022 International Congress

    Effect of freezing of gait and antiparkinsonian medication on joint kinematics and kinetics in gait in patients with Parkinson’s disease

    T. Shida, D. Campos, C. Oliveira, R. Treza, S. Hondo, E. Los Angeles, C. Bernardo, L. Oliveira, M. Carvalho, D. Coelho (São Bernardo Campo, Brazil)

    Objective: This study aims to evaluate the interaction between FoG and antiparkinsonian medication on individuals with PD's kinematic and kinetic gait parameters. Background: Regarding Parkinson's…
  • 2022 International Congress

    DIFFERENT PATTERNS OF ACUTE SACCADIC RESPONSES TO LEVODOPA CHALLENGE TEST IN DE NOVO PARKINSON’S DISEASE: POSSIBILE PROGNOSTIC IMPLICATIONS

    C. Terravecchia, G. Mostile, CG. Chisari, A. Luca, R. Terranova, G. Donzuso, CE. Cicero, G. Sciacca, A. Nicoletti, M. Zappia (Catania, Italy)

    Objective: To explore possible different patterns of acute saccadic responses to Levodopa Challenge Test (LCT) in a de novo drug-naïve Parkinson’s Disease (PD) population and…
  • 2022 International Congress

    LFP beta frequency OFF-ON shift in subthalamic nucleus in Parkinson’s disease

    K. Sayfulina, V. Filyushkina, A. Gamaleya, E. Belova, A. Tomskiy, A. Sedov (Moscow, Russian Federation)

    Objective: The aim of the current study is to investigate the frequency characteristics of beta activity in Parkinson’s disease. We hypothesized that beta peak central…
  • 2022 International Congress

    Subcutaneous Foslevodopa/Foscarbidopa in Patients With Advanced Parkinson’s Disease: Results From a Randomized, Double-blind, Double-dummy Phase 3 Trial

    M. Soileau, M. Spindler, J. Aldred, K. Budur, N. Fisseha, V. Fung, A. Jeong, T. Kimber, K. Klos, I. Litvan, D. O’Neill, W. Robieson, D. Standaert, S. Talapala, E. Okeanis Vaou, H. Zheng, M. Facheris, R. Hauser (Georgetown, USA)

    Objective: To evaluate the efficacy and safety/tolerability of 24-hour/day continuous subcutaneous infusion (CSCI) of foslevodopa/foscarbidopa (a soluble formulation of levodopa/carbidopa prodrugs) vs oral levodopa/carbidopa in…
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