Instrumental Measurement of Stepping in Place – Detection of Asymmetry and Freezing of Gait
Objective: To detect freezing of gait (FoG) and quantify movement asymmetry from markerless full body motion capture with Microsoft Kinect™ during the execution of a…Predictive Ability of Clinical Timed Tests for Postural Instability and Gait Difficulty in Parkinson’s Disease
Objective: To identify clinical determinants for postural instability and gait difficulty in persons with Parkinson's disease (PD). Background: Gait deficits and postural instability in persons…The combination of clinical scales and walking measures to predict falls in Parkinson’s disease: Does the length of the prospective follow-up period matter?
Objective: This study aimed: (i) to identify the best combination of clinical scales and walking measures to predict falls in people with Parkinson’s disease (PD)…Management of fragility fractures in Parkinson’s Disease (PD)
Objective: To assess the management of osteoporotic fragility fractures in patients with PD attending a Movement disorders clinic. Background: Patients with PD have a high…Falls characteristics of male and female patients with Parkinson’s disease (PD)
Objective: To compare Falls risk characteristics in male and female PD patients attending a multidisciplinary Movement disorders clinic. Background: Parkinson’s disease is commoner in males.…A combined cognitive and motor exercise program for people with Parkinson’s disease and Freezing of gait; a pilot study.
Objective: The purpose of this pilot study was to explore whether this combined cognitive and motor exercise program would 1) improve freezing of gait (FOG)…A novel C. elegans model for identification of small molecules that target alpha-synuclein-mediated toxicity
Objective: To develop a novel transgenic C. elegans model to study dopaminergic neurodegeneration mediated by alpha-synuclein. Background: Targeting alpha-synuclein could be a disease-modifying strategy for…Neural mechanisms underlying step initiation failure in patients with Parkinson’s disease and freezing of gait
Objective: To investigate the neural mechanisms underlying gait initiation failure in Parkinson's disease patients with Freezing of Gait. Background: Freezing of Gait (FOG) is a…Modulation of local field potentials during gait in the STN of patients with Parkinson’s disease
Objective: PD patients with implanted DBS electrodes allow for the investigation of basal ganglia activity during gait. Background: Whereas the overall spectral content of local…Optogenetic silencing of locus coeruleus activity in mice impairs cognitive flexibility in an attentional set-shifting task
Objective: In this study we used unilateral optogenetic silencing of the LC in an attentional set-shifting task (ASST) to evaluate the influence of the LC…
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