Diagnostic Accuracy of NPH by Radiographic Suspicion and Effect on Patient Outcomes
Objective: Our study examines the radiographic accuracy when suggesting normal pressure hydrocephalus (NPH), correlation with imaging study indication, and frequency of lumbar puncture (LP) for…Impaired Cortical Compensation in GBA1-Associated Parkinson’s Disease
Objective: To test whether GBA1 mutations are associated with impaired cortical compensation in Parkinson’s disease (PD) using a unique 2x2 design to parse the effect…Amyloid Burden in the Precuneus and Posterior Cingulate Gyrus Is Associated With Cognitive Function and White Matter Microstructure in Lewy Body Dementia
Objective: To investigate the relationship between amyloid burden measured by PET and white matter microstructural alterations assessed by advanced diffusion MRI in individuals with Parkinson’s…Microstructural cortical alterations are related to cognitive and disease severity in progressive supranuclear palsy
Objective: To study cortical microstructural alterations in patients with progressive supranuclear palsy (PwPSP) and their associations with both cognitive and clinical symptoms. Background: Midbrain’s atrophy on structural…Microstructural and functional abnormalities of Amygdala subregions in Parkinson’s Disease with impulse control disorder
Objective: To investigate amygdala subregional alterations associated with impulse control disorders (ICD) in Parkinson’s disease (PD) and to clarify the mechanistic role of the superficial…Cortical–Subcortical Structural Signature of dementia with lewy bodies Reveals Cognitive Trajectories of Lewy Body Disease in REM Sleep Behavior Disorder
Objective: We aimed to derive a DLB-related structural MRI pattern based on cortical and subcortical morphometry and investigate whether this pattern predicts phenoconversion and clinical…Topographic Heterogeneity of Dopaminergic Denervation and Iron Deposition in Functional Subregions of Nigrostriatal System in Parkinson’s Disease
Objective: To investigate the spatial relationship between striatal dopaminergic denervation and nigral iron accumulation in Parkinson’s disease (PD) using functional subregional parcellation. Background: Excessive nigral…Locus Coeruleus-Thalamic Circuit Degeneration in Parkinson’s Disease
Objective: This study characterizes the microstructural evolution of the locus coeruleus (LC) and its thalamic projection tract in Parkinson’s disease (PD) using free‑water imaging across…Clinical Significance of Automatically Assessed Perivascular Space Count in Subcortical White Matter of Parkinson’s Disease
Objective: This study aimed to examine the relationship between automatically quantified perivascular space (PVS) count located in the subcortical white matter (WM), baseline motor deficits,…Microstructure predicts cognition after Neurostimulation in Parkinson’s disease
Objective: To identify preoperative microstructural markers that are associated with postoperative changes in cognition. Background: Subthalamic deep brain stimulation (STN-DBS) represents an established therapeutic intervention…
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