fMRI Activity during Working Memory Manipulation is Associated with Caudate Integrity in Early Parkinson’s Disease
Objective: This study aimed to determine whether reduced dopaminergic integrity and increased iron deposition in the caudate are associated with altered BOLD activation during high…Diffusion MRI Evidence of Cerebellar Involvement in Cognitive Dysfunction in Parkinson’s Disease
Objective: To determine whether cerebellar axonal microstructural abnormality is associated with cognitive performance in PD. Background: Cognitive impairment in Parkinson’s disease (PD) often affects executive…Coupling between global BOLD signal and cerebrospinal fluid flow in isolated REM sleep behavior disorder and its relation with non-motor symptoms.
Objective: To explore changes in global BOLD (gBOLD) signal and cerebrospinal fluid flow (CSF) coupling in isolated REM sleep behavior disorder (iRBD) as a Magnetic…Structural-Functional Coupling Supporting Motor Reserve in Early-Stage Parkinson’s Disease
Objective: To explore whether motor reserve in early Parkinson's disease (PD) is related to structural-functional coupling (SFC) Background: Motor reserve contributes to individual variability in…Cross-Sectional and Longitudinal MRI Biomarkers of Neurodegeneration in Friedreich’s Ataxia
Objective: - To identify structural CNS changes associated with Friedreich’s ataxia (FRDA).- To characterize their longitudinal progression. Background: Friedreich’s ataxia (FRDA), the most common inherited…Genetic Architecture Of Intracranial Brain Calcification: A Systematic Review
Objective: To systematically identify monogenic disorders associated with intracranial intraparenchymal brain calcification and synthesise their clinical, radiological and molecular features. Background: Brain calcification is a…Regional Homogeneity in the Visual Network Mediates between Microbiota and Cognition in Parkinson’s Disease
Objective: We study the role of spontaneous brain activity in the cross-talk between gut microbiota and cognition in PD. Background: Gut dysbiosis is a prevalent…Investigating Substantia Nigra Microstructural Integrity as a Potential Predictive Biomarker for Fall Burden in Parkinson’s Disease
Objective: Determine whether baseline Diffusion Tensor Imaging (DTI) measures of the substantia nigra (SN) predict fall incidence and burden in Parkinson’s disease (PD). Background: Degeneration of dopaminergic…Can Parkinson’s Disease and Progressive Supranuclear Palsy be Distinguished Using Surgical Planning Image Analysis Software?
Objective: During deep brain stimulation (DBS), the surgical planning software Elements can automatically identify deep brain structures and calculate their volumes. This procedure is straightforward…Automatic Segmentation of the Subthalamic Nucleus and Globus Pallidus Internus: Can it support planning and programming in Deep brain stimulation
Objective: Whether auto-segmentation matches anatomy?Whether auto-segmentation volume difference in either side matches UPDRS score difference between two sides?whether auto-segmentation volume depends on MRI sequence?Whether auto-segmentation…
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