Investigate the association of MAPT haplotype and neuroanatomical structure and its influence on the risk of Parkinson’s disease
Objective: To investigate if the vulnerability of Parkinson’s Disease (PD) can be reflected in the neuroanatomical structure in different MAPT haplotype carriers. Background: It has…Longitudinal imaging of regional volumes, presynaptic terminals and glucose metabolism in brains of people with early Huntington’s disease
Objective: To compare the sensitivity of 11C‑UCB‑J PET, 18F-FDG PET and volumetric MRI for detection of longitudinal brain changes in early Huntington’s Disease (HD). Background:…Parkinsonism and dilated ventricles: not all hydrocephalus is normal-pressure
Objective: We discuss a patient with rapidly progressive parkinsonism with radiological features of normal pressure hydrocephalus, who was diagnosed with obstructive hydrocephalus secondary to intracranial…Neuroimaging analysis of postural instability in Progressive Supranuclear Palsy: a Voxel‐based morphometry approach
Objective: The aim of the study was to identify the mainly brain regions involved in postural instability (PI) in Progressive Supranuclear Palsy (PSP) with a…Cognitive flexibility associates with atrophy and disrupted connectivity of the cognitive cerebellum in degenerative cerebellar ataxia
Objective: This study was to investigate the features of cognitive flexibility in patients with degenerative cerebellar ataxia, and to identify the pathophysiological correlates of cognitive…Habenula Volume in Mood Disorders in Parkinson’s Disease
Objective: To assess whether dysregulation of habenula (Hb) contributes to mood disorders in Parkinson’s disease (PD). Background: PD is often accompanied by mood disorders, such…Accelerated longitudinal brain atrophy in the ‘diffuse malignant’ Parkinson’s disease subtype
Objective: To investigate differential pattern of brain atrophy between Parkinson’s disease (PD) clinical subtypes using longitudinally acquired brain magnetic resonance imaging (MRIs). Background: Parkinson’s disease…Leveraging MRI and machine-learning for early detection of cognitive impairment in Parkinson’s disease
Objective: To develop a machine learning model using MRI data that predicts the likelihood of cognitive impairment in newly diagnosed patients with Parkinson's disease (PD).…Contribution of MRI and machine learning approaches to the diagnosis of patients with early-stage parkinsonism in a situation of clinical uncertainty
Objective: To determine whether MRI and machine learning approaches improve diagnostic accuracy in patients with early-stage parkinsonism compared to clinical criteria Background: Parkinson’s disease (PD)…Imaging the noradrenergic system in Parkinson’s disease: A [11C]Yohimbine PET and neuromelanin MRI study
Objective: To assess two aspects of the noradrenergic system using multimodal in vivo imaging in a sample of Parkinson’s disease (PD) patients and healthy controls…
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