Automatic Detection of Nigrosome Degeneration in Susceptibility-Weighted MRI for Computer-Aided Diagnosis of Parkinson’s Disease Using Machine Learning
Objective: Automatize the detection of ‘swallow-tail’ appearance in substantia nigra dopaminergic neurons using MRI for more robust tests on Parkinson’s disease (PD) diagnosis. Background: Differential…Frailty as clinical modulator of brain damage and progression in Parkinson’s disease
Objective: To evaluate the prevalence of frailty and correlation with motor and non-motor symptoms as well as MRI atrophy and white matter hyperintensities in Parkinson's…Prevalence of apathy in Indian patients with Parkinson’s disease and its correlation with nigrosomal imaging
Objective: To assess the prevalence of apathy in patients with patients with Parkinson's disease and to correlate it with nigrosomal imaging in a subset of…Higher grey matter aging in multiple system atrophy than Parkinson’s disease
Objective: To investigate the “brain age” signature in multiple system atrophy (MSA) and Parkinson's disease (PD), and its correlation with motor and cognitive performance. Background:…Investigating Substantia Nigra Damage using Fully Automated Segmentation of Neuromelanin MRI in Early Parkinson’s Disease
Objective: Development of reliable imaging biomarkers of dopaminergic cell neurodegeneration is crucial to facilitate therapeutic drug trials in Parkinson's disease (PD). Neuromelanin-sensitive (NM) MRI techniques…The clinical significance of the swallow tail sign in distinguishing Parkinson’s disease patients from healthy individuals
Objective: To investigate whether the absence of the swallow tail sign can be applied for distinguishing PD patients from healthy individuals. Background: With conventional MRI,…Anxiety in Parkinson’s disease is associated with changes in the brain fear circuit
Objective: The aim of this study was to identify the anatomical and functional changes related to anxiety, especially in the “fear circuit”, by comparing PD…7 Tesla MRI investigation of cortical thickness in patients with Huntington’s disease and age-matched healthy controls
Objective: Evaluate cortical thickness in Huntington's disease (HD) using 7 Tesla (T) MRI. Background: There are currently no effective disease-modifying therapies for HD. In order…Tractography of the corticospinal tract in Parkinson’s disease. How does diffusion values vary along tract segments?
Objective: To assess diffusion tensor imaging differences between PD patients and healthy controls in 8 corticospinal tract segments. Background: Parkinson’s disease (PD), despite having motor and…Dual hit model of Parkinson’s disease propagation using MRI biomarkers and partial least squares path modeling
Objective: This study aimed using multimodal MRI to test two models of Parkinson’s disease propagation and investigated how the models were influenced by the presence…
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