In-vivo free-water imaging and functional connectivity in a knock-in mouse model of DYT1 dystonia
Objective: To examine in-vivo functional connectivity and free-water diffusion imaging in dystonic mutant Tor1a knock-in (DYT1) and wild-type (WT) control mice. We test the hypothesis…Manual MRI morphometry in Parkinsonian syndromes
Objective: We investigated a large sample of Parkinsonian patients and healthy controls from five German academic medical centers with 3D MP-RAGE sequences on mainly 3T…Is levodopa-induced dyskinesia in Parkinson’s disease associated with increased blood brain barrier permeability and volumetric changes?
Objective: The aim of this study was to explore the angiogenetic hypothesis for Levodopa-induced-dyskinesia (LID) using advanced MRI methods in patients with Parkinson's disease (PD).…Cerebellar GABA in essential tremor and dystonic tremor: A MR spectroscopy study
Objective: To explore the role of GABA in the pathophysiology of ET and DT by using MR spectroscopy. Background: The mechanisms of tremor in ET…Progressive atrophy of parahippocampal gyrus correlates with Hoehn & Yahr stages of Parkinson’s disease: A voxel based morphometric study
Objective: To determine the gray matter (GM) changes in different clinical stages of Parkinson's disease (PD) using Voxel Based Morphometry (VBM). Background: PD is a…Detecting brainstem changes in Parkinson’s disease using quantitative MRI
Objective: 1. Can brainstem changes be detected using quantitative MRI (qMRI). 2. How many subjects would be required to detecting changes in brainstem regions affected…Striatal postsynaptic dysfunction in X-linked dystonia-parkinsonism is associated with disease progression
Objective: To assess pre- and postsynaptic dopaminergic function in X-linked dystonia-parkinsonism (XDP). Background: X-linked dystonia-parkinsonism (XDP) is a neurodegenerative adult-onset movement disorder associated with striatal…Children with intractable temporal and extratemporal seizures: Correlation of the MR spectroscopy and EEG findings in the surgical planning
Objective: To show the value of MR spectroscopy in detecting metabolite ratios dysfunction and in lateralizing the epileptogenic focus in agreement with EEG in children…Relative hypoglycemia induces acute chorea followed by chronic parkinsonism in a diabetic patient on hemodialysis: A case with sequential clinico-radiological correlate
Objective: To present a sequential clinico-radiological study of a diabetic patient on hemodialysis who developed acute chorea followed by chronic parkinsonism. Background: Hyperglycemic chorea is…Severe striatal and pallidal atrophy in early disease stages of X-linked dystonia-parkinsonism
Objective: To investigate cortical and subcortical atrophy patterns in X-linked dystonia-parkinsonism (XDP). Background: XDP is a neurodegenerative disorder characterized by severe adult-onset dystonia followed by…
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