“Grab-the-lock test “ – A novel clinical test for identification of dorsolateral Subthalamic nucleus [STN] during deep brain stimulation [DBS]
Objective: The target during STN DBS for Parkinson’s disease is the dorsolateral STN which plays a major role in motor functions in contrast to the venteromedial…Movement-related modulation of beta/high frequency oscillations and low-beta pallido-cortical coherence in Parkinson’s disease.
Objective: To characterize changes in synchronized oscillatory activity and coherence between the globus pallidus (GPi) and primary motor cortex (M1) of Parkinson’s disease (PD) patients…Fundamental changes in Nerve Conduction Velocity and hyperpolarization latency of action potential of Sciatic nerve at the pre-motor phase in a chronic PD in vivo model: a neurotool for Parkinson’s disease diagnosis
Objective: To evaluate the changes in NCV and hyperpolarization latency of action potential of Sciatic nerve at the pre-motor phase in MPTP induced chronic PD…Validation of Direct/Indirect targets with intra-operative clinical assessment in the Indian population & comparison with image guided and MER based targeting for Subthalamic Nucleus(STN) based Deep Brain Stimulation(DBS) in Parkinson’s disease(PD)
Objective: This study attempts to validate the relationship between Direct-D, indirect-ID coordinates for STN in Indian subjects. Also, this study tries to compare the D,…Electrophysiology marker of levodopa induced dyskinesia in Parkinson disease
Objective: To review various electrophysiology markers of levodopa induced dyskinesia (LID) investigated in current studies and the pathophysiology of LID in the context of abnormal…Pallidal firing rate and alpha oscillations correlate with the severity of clinical symptoms in patients with dystonia
Objective: To examined how pallidal activity correlates with symptom severity across dystonic patients. Background: The internal segment of globus pallidus (GPi) is the most common…Oscillatory activity of pause-burst STN neurons shows an association with motor symptoms of Parkinson’s disease
Objective: Here we aimed to investigate heterogeneity in the neuronal activity within the subthalamic nucleus (STN) to search the association between oscillatory activity and motor…Machine learning supervised classification study for Parkinson`s disease progression through graph-based feature selection method
Objective: The model helps neuro physicians/ neurologists to improve the PD symptoms, or therapeutic-treatment planning-procedures. Background: Artificial intelligence-based machine learning (AI-ML) supervised classification systems have…Specificity of neuronal activity in globus pallidus in patients with DYT1 dystonia
Objective: The aim of this study was a comparative analysis of the neuronal activity of globus pallidus in patients with DYT1 dystonia and idiopathic dystonia.…Intraoperative microelectrode recodings reveal functional structure of Globus Pallidus pars interna in dystonic patients
Objective: We characterized the functional structure of Globus pallidus pars interna (GPi) in dystonic patients by analizing the distribution of the firing pattern features in…
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