Manifestations of aging and Parkinson’s Disease in low-frequency fluctuations of postural sway velocity
Objective: To distinguish the effects of aging and Parkinson's disease on balance control. Background: Many balance control measures are derived from spontaneous fluctuations of the center…Neurologic Music Therapy (NMT) and Non-Invasive Stimulation for Upper Extremity Performance in Patients with Corticobasal Syndrome (CBS)
Objective: To investigate if NMT with or without non-invasive brain stimulation can improve upper limb performance in patients with corticobasal syndrome Background: Previous research suggests…A randomized, phase 2a, double-blind, placebo-controlled clinical trial with NE3107 adjunctive to carbidopa/levodopa in patients with Parkinson’s disease
Objective: To evaluate the motor effects of NE3107 treatment in patients with levodopa-treated Parkinson’s disease (PD) experiencing motor fluctuations. Background: NE3107 is an oral, blood-brain…Stability and predictability of motor symptom control in patients with advanced Parkinson’s disease (aPD) receiving continuous subcutaneous foslevodopa/foscarbidopa (LDP/CDP)
Objective: To evaluate temporal changes in motor states (OFF and ON without troublesome dyskinesia [TD; good ON]) throughout the waking day in patients with aPD…Nocturnal behavior of people with Parkinson’s disease
Objective: Compare the nocturnal energy expenditure (kcal) and activity behavior of people with PD using a real-time wearable sensor, and determine whether these outcomes differed…Influence of Cognitive Function on Obstacle-Crossing Performance in People with Parkinson’s Disease: A Cross-Sectional Study
Objective: This study investigated the influence of cognitive function on obstacle crossing performance in people with Parkinson's disease (PD). Background: Obstacle-crossing is a complex motor…Potential role of Alpha-synuclein levels in Platelets in GBA-related PD
Objective: Identification of a blood biomarker to predict PD diagnosis or to monitor the disease progression. Background: Previous evidence suggests differences in systemic alpha-synuclein levels…Effects of NE3107 anti-inflammatory treatment on motor activity and neurodegenerative features of Parkinson’s disease in a marmoset monkey model
Objective: To demonstrate the effects of an oral, anti-inflammatory agent, NE3107, on motor activity, levodopa-induced dyskinesia (LID) induction, and neuron survival in a marmoset model…Association between fine motor function and brain structure: Findings from the population-based Rhineland Study
Objective: To examine the relation between brain structure and fine motor function across adult lifespan in a large cohort study. Background: Decreased fine motor function…Education and the motor effects of dopamine loss in Parkinson’s disease
Objective: To examine the relation between education and dopamine signal loss in PD. Background: In support of the cognitive reserve concept, it has consistently been…
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