The Associations between Cognitive Reserve Proxies, Multimodal MRI Brain Measures and Cognition, Motor Function and Mood in Parkinson’s Disease
Objective: This study aimed to use multimodal MRI to explore the relative importance of cognitive reserve (CR) proxies, compared to CR- and Parkinson’s disease (PD)-related…The Efficacy of Neuromodulation for Motor Recovery in Children with Hemiparesis Due to Perinatal Stroke: A Systematic Review and Meta-Analysis.
Objective: To assess the effectiveness of neurostimulation in enhancing motor function in children with perinatal stroke and hemiparetic cerebral palsy. Background: Neuromodulation techniques, including repetitive…A Phase II Randomized, Parallel, Double-blind, Placebo-controlled Study of the Efficacy and Safety of WD-1603 in Subjects with Parkinson’s Disease
Objective: To investigate the effectiveness, safety and pharmacokinetics of WD-1603 carbidopa-levodopa controlled-release tablets in subjects with Parkinson's disease. Background: The development of drug products that…Brain hemodynamic responses to a motor control paradigm in younger and older adults, and people with Parkinson’s Disease: An fNIRS mediated feasibility study.
Objective: This study aims to investigate the use of fNIRS in measuring the hemodynamic response of the brain during motor control tasks of increasing complexity…Yawning Associated Parakinesia Brachialis Oscitans, Penile Erection, and Truncal Seizures Following Intracerebral Hemorrhage
Objective: To describe a rare case of parakinesia brachialis oscitans (PBO) with yawning-associated penile erection and truncal seizures in a patient with a right middle…Cognitive Load Modulates Excitability of Subthalamic Motor Circuitry in Parkinson’s Disease
Objective: To characterize the effect of cognitive load on the excitability of circuitry connected with the subthalamic nucleus (STN) motor territory in Parkinson’s disease (PD)…Prevalence and Characteristics of Glucocerebrosidase Genetic Variants in Nepalese Early-onset Parkinson’s Disease Patients
Objective: To evaluate the genotype and phenotype of early-onset Parkinson´s Disease (EOPD) in the Nepalese population. Background: A significant proportion of early-onset PD (EOPD) can…The cerebellum encodes dynamic motor frequencies for volitional movements
Objective: Investigate how the cerebellum computes and regulates motor precision during daily movements Background: Motor coordination, ensuring movement precision and reliability, is governed by the…Does the cerebellum compensate to enable motor learning in Parkinson’s Disease?
Objective: To test the causal relation between cerebellar function and learning in PD. Background: Neuroimaging studies reveal that people with Parkinson’s disease (PwPD) exhibit increased…Local field potential vs image guided programming: clinical trial for optimization the deep brain stimulation in Parkinson’s disease
Objective: To determine the most effective and efficient STN-DBS programming method in PD comparing LFP-GP and IGP focusing on motor improvement, quality of life and…
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