Decoding Naturalistic Movement for Adaptive Deep Brain Stimulation in Parkinson’s Disease
Objective: To demonstrate the proof-of-concept of a closed-loop deep brain stimulation (DBS) policy designed to reduce slowness in Parkinson’s disease (PD) by increasing stimulation amplitudes…Neuroprotective Effects of Co-Administered Hesperetin and Resveratrol Nanoparticles on Oxidative Stress and Neurobehavioral Deficits in Parkinson’s Disease
Objective: This study aimed to evaluate the therapeutic potential of solid lipid nanoparticles (SLNs) containing hesperetin (HE-SLN), resveratrol (RE-SLN), and their co-administration (HE-RE-SLN) in combating…Therapeutic Potential of GLP-1 Receptor Agonists in Parkinson’s Disease: A Systematic Review and Meta-Analysis
Objective: To assess the safety and effectiveness of GLP-1 RAs in patients with PD. Background: Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by…Perinatal Dioxin Exposure and Dopaminergic Vulnerability in the Development of Motor Dysfunction Sequelae
Objective: To investigate the impact of dioxins on movement disorder development and the mechanisms increasing vulnerability to future motor dysfunction. Background: Dioxins are persistent organic…Single- and Multi-Unit Activity in STN Provides Enhanced Insight into Speech-Related Neural Dynamics in Parkinson’s Patients
Objective: We aimed to elucidate neural representations in local field potentials (LFP) and single- and multi-unit activity of subthalamic nucleus (STN) neurons during speech tasks,…Boosting Education and Awareness Together for people with Parkinson’s Disease (BEATs-PD): Methodological Considerations in Research Co-Creation
Objective: To describe methodological considerations related to stakeholder engagement in community-based participatory research (CBPR) to create a dance and music-based program (DMBP) for people with…Daily Activity Analysis of Parkinson’s Disease Using Machine Learning with 3D Poses
Objective: This study aims to find a digital behavioral marker Parkinson’s disease (PD) in activities of daily living via machine learning (ML) analysis of 3D…Dose Optimization of Foslevodopa/Foscarbidopa: Post Hoc Analysis of Study Completers
Objective: To describe dose optimization, efficacy, and safety of foslevodopa/foscarbidopa (LDp/CDp) in patients with advanced Parkinson’s disease (PwaPD) who completed a 52-week open-label study. Background:…Characterization of neuronal exosomes purified from plasma of Parkinson’s Disease Chilean patients
Objective: The diagnosis of PD is usually late and has only palliative treatments that seek to slow the progression of motor symptoms. These characteristics make…Automatic Intelligibility Rating in Parkinson’s Disease: A Multilingual Approach
Objective: To investigate the validity and robustness of an automatically generated intelligibility score in Parkinson’s disease (PD) across multiple languages. Background: 90% of people with…
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