Next-generation sequencing analysis of circulating microRNAs in multiple system atrophy
Objective: The discriminatory peripheral circulating small non-coding RNAs (sncRNAs) using next-generation sequencing (NGS) between patients of multiple system atrophy (MSA), Parkinson's disease (PD), and healthy controls…The pivotal difference in gut microbiota between multiple system atrophy and Parkinson’s disease
Objective: The knowledge gap between microbiome dysbiosis and pathogenesis of multiple system atrophy (MSA) remains. Background: Mounting evidence has found significant alterations in the gut…Association between sleep apnea and prognosis in patients with multiple system atrophy
Objective: We aimed to investigate the relationship between sleep apnea and survival or early frequent falls in patients with multiple system atrophy (MSA). Background: Sleep-disordered…The study of clonidine growth hormone study amongst definite MSA, PD, PSP, and PAF patients to assess its feasibility as a future non-invasive biomarker
Objective: To analyze the sensitivity and specificity of the clonidine growth hormone (CGH) to distinguish probable multiple system atrophy (MSA) from pure autonomic failure (PAF),…Mosaicism for somatic SNCA copy number variants in multiple system atrophy is related to pathological subtype and presence of α-synuclein inclusions
Objective: To investigate the correlation of somatic copy number variants (CNVs) of the alpha-synuclein gene (SNCA) in multiple system atrophy (MSA) with disease subtype, and…A clinico-genetic study based on the Innsbruck MSA Registry
Objective: To assess family history (FH) for neurodegenerative disorders in people with multiple system atrophy (MSA), compare its prevalence with that of a prospectively recruited…Comorbid neuropathological features in multiple system atrophy
Objective: To elucidate the distribution of comorbid neuropathology in multiple system atrophy (MSA) and its clinical correlation. Background: Multiple protein accumulations are often present in…An Eye of a Tiger cannot see all the true: a case series.
Objective: Describe patients with Multiple System Atrophy with iron accumulation in neuroimaging of striatal regions. Background: MSA is an adult neurodegenerative disease with parkinsonism, cerebelar…Alteration of lysosomal enzymatic activities in patients with multiple system atrophy
Objective: To estimate whether alteration of lysosomal activities contributes to synucleinophaties pathogenesis. Background: Multiple system atrophy (MSA) belongs to a group of neurodegenerative disorders termed synucleinopathies, which also include Parkinson's disease (PD)…Plasma Short-Chain Fatty Acids Differences in Multiple System Atrophy from Parkinson’s Disease
Objective: We aimed to investigate the plasma short-chain fatty acids (SCFAs) in multiple system atrophy (MSA) patients and to identify the potential differential diagnostic ability.…
