Physical Therapy Role with Differential Diagonosis and Treatment with Dizziness and Multiple System Atrophy: A Case Study
Objective: The purpose of this case study is to address the role of physical therapy (PT) in a case of complex dizziness, progressive symptoms, and…Considerations before initiating therapy in Parkinsonism: basing on the health-related quality of life.
Objective: We aimed to compare the determinants of life quality between drug naïve PD and MSA-P patients. Background: To improve the quality of life (QoL)…High Content Screening of synucleinopathy in primary cortical neurons : dissecting out the interplay between the basic synuclein pools
Objective: To set up a robust (see ref 1 for definition) 96-well High Content Screening assay of synucleinopathy in primary cultures of cortical neurons. Background:…Continuous dopaminergic treatment with levodopa/carbidopa intestinal gel in multiple system atrophy: report of three patients
Objective: To evaluate the effect of continuous dopaminergic treatment with levodopa/carbidopa intestinal gel (LCID) on motor and non-motor symptoms in multiple system atrophy (MSA) patients.…Preferred place of death (PPOD) in PD, PSP and MSA
Objective: To ascertain whether people with PD, PSP and MSA have a PPOD Background: Achieving a PPOD is felt to be an important factor in…Is safinamide helpful in multiple system atrophy?
Objective: To retrospectively review the clinical benefit of safinamide in patients with Multiple System Atrophy. Background: Safinamide is a new monoamine oxidase-B inhibitor, with dopaminergic…A First in Human Study of PBT434, a Novel Small Molecule Inhibitor of Alpha-Synuclein Aggregation
Objective: To evaluate the safety, tolerability and pharmacokinetics of PBT434 in healthy volunteers. Background: PBT434 is a novel, small molecule inhibitor of alpha-synuclein aggregation. In…PBT434 prevents the accumulation of glial cell inclusions and insoluble alpha-synuclein in a mouse model of Multiple System Atrophy
Objective: To evaluate PBT434 in a transgenic mouse model of multiple system atrophy (MSA) Background: PBT434 is a novel quinazolinone inhibitor of iron-mediated protein accumulation…Effects of multi-session repetitive transcranial magnetic stimulation on performance of motor control and dynamics of spontaneous brain activity in multiple system atrophy
Objective: To explore the effectiveness of repetitive transcranial magnetic stimulation (rTMS) on performance of motor control and dynamics of spontaneous brain activity in multiple system…Caregiver Burden in a Multidisciplinary MSA Clinic
Objective: To explore the correlation between disease and caregiver burden in MSA. Background: For patients with Multiple System Atrophy (MSA), the increasing loss of independence…
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